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Bispectral index
How to interpret the BIS values
The Bispectral Index is an absolute value, so baseline information about the patient
is not required for BIS monitoring. The following table lists the BIS values and their
significance.
BIS value Clinical endpoint
Comments
100
Awake Patient responds to normal voice
80
Light/moderate sedation Patient responds to loud commands
or mild prodding/shaking
40 to 60
General anesthesia Patient has low probability of explicit
recall and is unresponsive to verbal
stimulus
20
Deep hypnotic state EEG suppression, or burst suppression
as it is sometimes referred to, is an
easily recognizable EEG pattern
characterized by bursts of activity
of varying shape alternating with
episodes of flatline activity.
0
Isoelectric EEG No brain activity detected
This chart reflects a general association between clinical state and BIS values. Ranges
are based on results from a multi-center study of the BIS involving the administration
of specific anesthetic agents. BIS values and ranges assume that the EEG is free of
artifact that can affect its performance.
Titration of anesthetics to BIS ranges should be dependent upon the individual goals
for hypnotic state that have been established for each patient. These goals and
associated BIS ranges may vary over time and in the context of patient status and
treatment plans.
Low BIS values (below 40) may indicate overdosing of hypnotic medication, and high
BIS (over 60 to 65) may indicate too low concentrations of the drug.
BIS troubleshooting
Problem Solution
Measurement does not start
●
Check sensor attachment to the patient and the sensor placement.
●
Check the sensor’s contact with skin.
●
Check the sensor type.
●
Check all cable connections.
●
Check the digital signal processing unit.
BIS signal is poor
●
Check the sensor’s contact with skin.
●
Check the sensor.
●
Ensure that the digital signal processing unit is not close to any
electrical radiating equipment.
2062971-001 CARESCAPE Modular Monitors 399