Beckman Coulter Multisizer 4, User Manual

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PN A51387A
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Analyzer Overview
Overview
Automatic Blockage Detection
The Multisizer 4 automatic blockage detection feature monitors analysis runs for aperture blockage
and can automatically unblock the aperture and continue a run without operator intervention. The
Multisizer 4 allows the operator to select blockage detection settings based on current run data or
reference runs, view a blockage monitoring graph during analysis runs, and review blockage
monitoring data after a run is complete.
Extended Dynamic Range
The Multisizer 4 is capable of measuring particles in the range of 2% to 80% of the aperture diameter,
and in the range of 10% to 80% of the aperture diameter for a 2000-µm aperture tube. The standard
range is 2% to 60%; an extended dynamic range of 60% to 80% is available to examine broad
distributions that extend above the 60% threshold. This feature is intended for examining particles
in the small “tail” of a distribution that extends above 60%. For best results and to minimize
blockage, it is recommended to use a larger aperture size for samples that contain a significant
concentration of particles above 60% of the aperture diameter.
Multisizer 4 Components
The convenient design of the Beckman Coulter Multisizer 4 places the Sample Compartment,
Control Panel, and Electrolyte and Waste Jars at the front of the instrument.
Analyzer components are labeled in Figure 1.1 (below).
Figure 1.1 Multisizer 4 Analyzer Components
A Sample Compartment
B Control Panel
C Waste and Electrolyte Jar Compartment
D Electrolyte Jar
E Waste Jar