Beckman Coulter Multisizer 4, User Manual, Page: 10 / 238

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Table of Contents
Purging the Metering Pump , 9-2
Adjusting the Metering Pump , 9-3
Setting the Vacuum Regulator , 9-3
Measuring Gain Stage Offsets , 9-3
Setting Custom Measurement Intervals , 9-4
System Error: Unable to Measure Gain Stage Offsets , 9-4
Resolving Error Messages on Software Startup , 9-5
Viewing Advanced Multisizer Settings , 9-6
Waste Tank Settings , 9-6
Calibrating Waste Tank Sensors , 9-6
Vacuum Settings , 9-7
Flow Rate Error Messages , 9-8
Adjusting Volumetric Flow Settings , 9-8
Fill, Flush, and Drain Settings , 9-9
Viewing System Flush Time , 9-9
Draining the System , 9-11
Aperture Resistance Settings , 9-12
Calibrating the Electrolyte and Waste Jars , 9-13
Working with Field Service , 9-15
Requesting Service and Technical Support , 9-15
Identifying the Instrument , 9-15
Updating Firmware and FPGA Software , 9-16
Viewing the Instrument Schematic , 9-17
Viewing the Error Log , 9-18
Opening Service Mode , 9-18
CHAPTER 10:
Regulatory Compliance , 10-1
Regulatory Compliance , 10-1
Electronic Signatures (21 CFR Part 11) , 10-1
Electronic Records , 10-1
FDA Requirements , 10-1
Security Controls , 10-2
Electronic Controls , 10-2
System Validation , 10-2
Audit Trail , 10-3
File History and Audit Trail , 10-3
Accessing File History , 10-3
Setting Audit Trail Options , 10-4
Maintaining Electronic Signatures , 10-5
Generating Electronic Signatures , 10-5
Applying Electronic Signatures , 10-6
Additional Security Features , 10-7
Starting the Multisizer 4 with Security Enabled , 10-7