Continuous Mononuclear Cell Collection (CMNC) Procedures
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Spectra Optia Apheresis System Operator’s Manual
Functional Description of a Continuous Mononuclear Cell
Collection (CMNC) Procedure
During a CMNC procedure, the system pumps the patient’s blood into the tubing set and spins the centrifuge at
the speed required to target the optimal (default) packing factor of 4.5. The AIM system adjusts the flow rate of the
plasma pump to control the concentration of cells that flow through the collect port (based on the collection
preference). When the AIM system detects cells in the collect port, the system sounds a tone, the collect valve
moves into the collect position, and the collect pump pumps the mononuclear cells (MNC) into the collection bag.
The plasma pump pumps plasma out of the channel and either into the reservoir or into the plasma bag or the
collection bag, if plasma collection is targeted. The system always prioritizes collecting the MNC over collecting the
plasma. The red blood cells (RBC) are pushed out of the channel and into the reservoir, where they are combined
with the plasma for return to the patient.
Preparing to Perform a Procedure
Supplies
Assemble the supplies listed on page 62 before you begin a procedure.
Selecting the Procedure and Loading the Tubing Set
Follow the instructions starting on page 64 to select the procedure and load the tubing set. Before you load the
tubing set, verify that the set and the solutions you are using have not expired by checking the expiration date
printed on the packaging. Do not use an item if the current date is past the expiration date.
SpectraOptiaOpsManual.book Page 148 Thursday, May 17, 2018 11:24 AM
