Supplementary Information
266
Spectra Optia Apheresis System Operator’s Manual
Formula for Calculating Total Blood Volume (TBV)
TPE Procedures: Plasma and Platelet Removal Efficiency
Table A-1:
Formula
for calculating TBV (mL) using data in metric and English units
Metric
Female
183 + [356 × height
3
(meters)] + [33.1 × weight (kg)]
Male
604 + [367 × height
3
(meters)] + [32.2 × weight (kg)]
English
Female
183 + [0.005835 × height
3
(inches)] + [15 × weight (lb)]
Male
604 + [0.006012 × height
3
(inches)] + [14.6 × weight (lb)]
Sources:
Allen TH, et. al., “Prediction of Blood Volume and Adiposity in Man From Body Weight and Cube of Height.”
Metabolism
, 1956; 5, no. 3: 328-345.
Nadler SB, et al., “Prediction of Blood Volume in Normal Human Adults.”
Surgery,
1962; 52, no. 2:
224-232.
Table A-2:
Plasma and platelet removal efficiency for TPE procedures using the Spectra Optia system
Measure
Result (%)
Plasma removal efficiency
87.0 (mean)
Platelet removal efficiency
1.0 (median)
Source:
Tormey CA, et al., “Improved Plasma Removal Efficiency for Therapeutic Plasma Exchange Using a New Apheresis
Platform.”
Transfusion,
2010; 50: 471-477.
SpectraOptiaOpsManual.book Page 266 Thursday, May 17, 2018 11:24 AM
