Therapeutic Plasma Exchange with a Secondary Plasma Device (TPE-SPD) Procedures
98
Spectra Optia Apheresis System Operator’s Manual
Functional Description of a Therapeutic Plasma Exchange With a
Secondary Plasma Device (TPE-SPD) Procedure
During a TPE-SPD procedure, the system pumps the patient’s blood into the tubing set and spins the centrifuge at
the speed required to target the optimal (default) packing factor of 20. The AIM system monitors the interface
position and adjusts the flow rate of the plasma pump to maintain the optimal interface position for removing the
plasma. When the AIM system determines that the buffy coat has reached a specific thickness in the connector, or
when an inlet volume equal to 0.25 of the patient's TBV has been processed, the system slows the plasma pump
and flushes the buffy coat through the RBC port and into the reservoir.
The plasma pump pumps the plasma to the secondary plasma device. The treated plasma is then pumped into the
treated plasma bag. The replace pump pumps the contents of the treated plasma bag into the reservoir, where it
combines with the RBC and the cellular components from the channel for return to the patient. The system uses
the replace pump balance to manage the volume of plasma removed and the volume of plasma returned.
Preparing to Perform a Procedure
Supplies
Assemble the supplies listed on page 62 before you begin a procedure. You will also need the following additional
supplies:
•
Secondary plasma device (plasma device), as prescribed
•
Hemostats
•
Extension tubing set to use to connect the plasma device to the Exchange Set
•
Bag with a needle adapter to hold the treated plasma (treated plasma bag) and to attach to the outlet end of
the plasma device
Optional supplies:
•
Bag to use for fluid waste diverted from the plasma device
•
Connectors for connecting the treated plasma bag, the waste bag, or the tubing set to the plasma device. For
example:
• Two 3-way stopcocks or two Y-shaped connectors
• Male-to-male luer connector (optional)
Selecting the Procedure and Loading the Tubing Set
Follow the instructions starting on page 64 to select the procedure and load the tubing set. Before you load the
tubing set, verify that the set and the solutions you are using have not expired by checking the expiration date
printed on the packaging. Do not use an item if the current date is past the expiration date.
Warning:
Before performing a therapeutic plasma exchange procedure with a secondary plasma device
(TPE-SPD procedure), carefully review the instructions for use provided by the manufacturer of the secondary
plasma device.
SpectraOptiaOpsManual.book Page 98 Thursday, May 17, 2018 11:24 AM
