Waters Xevo G2 QTof, Operator'S, Overview And Maintenance Manual, Page: 151 / 248

Cleaning the APCI probe tip 5-75
Cleaning the APCI probe tip
Clean the APCI probe tip when you detect buffer buildup on the probe tip or
when the signal intensity weakens.
To clean the APCI probe tip:
1. On the Instrument Console system tree, click Xevo G2 QTof > Manual
optimization.
2. On the manual optimization page, click to stop the liquid flow.
3. Click Gas to start the desolvation gas.
4. Set Desolvation Gas to 650 L/h.
5. Set APCI probe Temp to 650 °C.
6. Click Operate .
7. Wait 10 minutes.
Rationale:
The high IonSABRE II probe heater temperature removes
any chemical contamination from the probe tip.
8. Click Standby .
Replacing the APCI probe sample capillary
Replace the stainless steel sample capillary in the APCI probe if it becomes
blocked and you cannot clear it, or if it becomes contaminated or damaged.
Removing the existing capillary
Required materials
• Chemical-resistant, powder-free gloves
• 7-mm wrench
• Combined 2.5-mm Allen wrench and cone extraction tool