Waters Xevo G2 QTof, Operator'S, Overview And Maintenance Manual, Page: 119 / 248

Cleaning the extraction cone 5-43
• Ultrasonic bath.
• Source of oil-free, inert gas (for example, nitrogen) for drying (air-drying
optional).
• Wash bottle containing HPLC-grade (or better) 1:1 methanol/water.
• Large beaker.
To clean the extraction cone:
1. Immerse the extraction cone in the glass vessel containing 1:1
methanol/water.
Tip:
If the extraction cone is obviously contaminated, use 45:45:10
methanol/water/formic acid.
2. Place the vessel in the ultrasonic bath for 30 minutes.
3. If you used formic acid in the cleaning solution, do as follows:
a. Rinse the extraction cone by immersing it in a glass vessel
containing water and then placing the vessel in the ultrasonic bath
for 20 minutes.
b. Remove any residual water from the extraction cone by immersing
it in a glass vessel containing methanol and then placing the vessel
in the ultrasonic bath for 10 minutes.
4. Carefully remove the extraction cone from the vessel, and blow dry it
using inert, oil-free gas.
Warning:
The extraction cone can be contaminated with
biohazardous and/or toxic materials. Always wear
chemical-resistant, powder-free gloves while performing this
procedure.
Warning:
Formic acid is extremely corrosive and toxic. Work with
extreme care, use a fume hood and suitable protective equipment.
Caution:
The extraction cone is fragile. Never place it on its tip; always
place it on its flanged base.
Caution:
To avoid recontaminating the extraction cone, wear
clean, chemical-resistant, powder-free gloves for the rest of this
procedure.