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  Maintenance and Service 

Page 166 

Charged Aerosol Detectors Corona Veo (RS) Operating Manual 

 

CAUTION—Spraying Solvent

 

Solvents can spray when under high pressure. 

 

Stop the pump flow prior to opening the flow path. 

 

Wait until the system pressure is down to zero. 

 

When opening the flow path, wear appropriate protective 
equipment. 

 

 

CAUTION—Hydrostatic Pressure 

Solvent may spill when you open the flow path. This is due to hydrostatic 
pressure in the system when the solvent reservoirs are located above 
the pump outlet. 
Before you loosen a connection in the flow path, turn off the pump flow 
and wait until the system pressure is down to zero. Unscrew the caps of 
the solvent reservoirs and remove the solvent lines together with the 
caps from the reservoirs. Empty the solvents lines. Refer to the 

Operating Manual

 for the pump. Retighten the reservoir caps. 

 

 

NOTICE—Detector Gas Flow and Pump Flow

 

Improper handling of detector gas flow and pump flow start and stop 
can damage the detector. Observe the respective order of steps: 

 

To stop pump flow and detector gas flow

 

Turn off the pump flow first, wait at least 5 minutes and only then 
turn off the detector gas flow. During the waiting period, the drain 
pump drains any remaining mobile phase to waste. 

 

To start detector gas flow and pump flow

 

Turn on the detector gas flow first, wait at least 5 minutes and only 
then turn on the pump flow. 

 

Содержание Corona Veo

Страница 1: ...Thermo Scientific Charged Aerosol Detectors Corona Veo Corona Veo RS Operating Manual 4820 8101 Revision 2 0 June 2017 thermoscientific...

Страница 2: ...except with the written authorization of Thermo Fisher Scientific Inc This manual is provided as is The contents of this manual are subject to being changed without notice in future revisions Thermo F...

Страница 3: ...ation or sales support for HPLC products contact your local Thermo Fisher Scientific sales organization For contact information go to Contact Us on http www thermofisher com Technical Assistance For t...

Страница 4: ...Contacting Us Page 4 Charged Aerosol Detectors Corona Veo RS Operating Manual...

Страница 5: ...ual 19 2 1 3 Safety Symbols on the Detector 20 2 1 4 Rating Plate 21 2 2 Intended Use 22 2 3 Safety Precautions 23 2 3 1 General Safety Information 23 2 3 2 Qualification of the Personnel 25 2 3 3 Per...

Страница 6: ...00 System 67 5 5 2 Setting Up Cable Connections to the Detector 69 5 5 3 Nebulizer Installation 77 5 5 4 Connecting the Gas Inlet and Exhaust Tubes 79 5 6 Setting Up the Liquid Flow Connections 81 5 6...

Страница 7: ...ue 145 6 7 7 Baseline Noise 146 6 7 8 Data Collection Rate 146 6 8 Software Operation 148 6 8 1 Setting Up the Detector in the Software 148 6 8 2 Operating the Detector from the Software 150 6 8 3 Sig...

Страница 8: ...the Detector 202 7 13 1 Preparing the Detector for Transport 203 7 13 2 Transporting the Detector to a New Location 203 7 13 3 Shipping the Detector 204 8 Troubleshooting 207 8 1 General Information...

Страница 9: ...ssories 244 10 4 Consumables and Replacement Parts 245 11 Appendix 247 11 1 Compliance Information 248 11 1 1 Declarations of Conformity 248 11 1 2 WEEE Compliance 250 11 1 3 FCC Compliance 251 11 1 4...

Страница 10: ...Contents Page 10 Charged Aerosol Detectors Corona Veo RS Operating Manual...

Страница 11: ...tectors Corona Veo RS Operating Manual Page 11 1 Using this Manual This chapter provides information about this manual the conventions used throughout the manual and the reference documentation that i...

Страница 12: ...notices that can prevent personal injury damage to the detector or loss of data when followed properly Note the following The detector configuration may vary therefore not all descriptions necessaril...

Страница 13: ...ich they apply They appear different from the main flow of text Safety messages are often preceded by an alert symbol and or alert word The alert word appears in uppercase letters and in bold type Mak...

Страница 14: ...Thermo Chromeleon 7 Services Manager Start Instrument Controller References and Messages References to additional documentation appear italicized Messages that appear on the screen are identified by...

Страница 15: ...7 Help and documents The Chromeleon 7 Help provides extensive information and comprehensive reference material for all aspects of the software For basic information about device installation and conf...

Страница 16: ...also to the user documentation provided by the manufacturers of third party components and materials for example Safety Data Sheets SDSs Third party documentation includes the user documentation for...

Страница 17: ...2 Safety Charged Aerosol Detectors Corona Veo RS Operating Manual Page 17 2 Safety This chapter provides general and specific safety information and informs about the intended use of the detector...

Страница 18: ...minor or moderate injury WARNING Indicates a hazardous situation that if not avoided could result in serious injury French Version Ce manuel comporte des consignes de s curit afin de pr venir tout ri...

Страница 19: ...mply with all safety messages and precautionary statements presented in this manual French Version Respectez les consignes suivantes Lisez le pr sent manuel attentivement avant toute installation ou u...

Страница 20: ...ates alternating current Indicates a terminal for protective grounding Indicates a terminal for functional grounding French Version Ce tableau r pertorie les symboles de s curit qui apparaissent sur l...

Страница 21: ...evice identification have the information from the rating plate available when communicating with Thermo Fisher Scientific French Version La plaque signal tique est plac e l arri re du d tecteur proxi...

Страница 22: ...tem is to analyze mixtures of compounds in sample solutions The detector is for use by qualified personnel and in laboratory environment only The detector is intended for laboratory research use only...

Страница 23: ...the replacement parts and additional components options and peripherals specifically authorized and qualified for the detector by Thermo Fisher Scientific Perform only the procedures that are describ...

Страница 24: ...es options et p riph riques sp cifiquement autoris s et certifi s pour le d tecteur par Thermo Fisher Scientific Ne r alisez que les proc dures d crites dans le pr sent manuel d utilisation et dans le...

Страница 25: ...ons Thermo Fisher Scientific recommends always having service personnel certified by Thermo Fisher Scientific perform the installation for brevity referred to as Thermo Fisher Scientific service engin...

Страница 26: ...ar Thermo Fisher Scientific par souci de concision appel es par la suite techniciens d entretien Thermo Fisher Scientific Si une personne autre qu un technicien d entretien agr par Thermo Fisher Scien...

Страница 27: ...data sheet provided by the vendor An eyewash facility and a sink should be available nearby If any substance contacts your skin or eyes wash the affected area and seek medical attention Protective Cl...

Страница 28: ...ivent se trouver proximit du syst me Si une substance quelle qu elle soit entre en contact avec vos yeux ou votre peau rincez abondamment la zone concern e l eau puis consultez un m decin V tements de...

Страница 29: ...quid reservoirs in the solvent rack that is available for the HPLC system AVERTISSEMENT D charge lectrique ou endommagement de l instrument Des tensions lev es sont pr sentes dans l appareil et peuven...

Страница 30: ...ure that you know the properties of all substances that you are using Avoid exposure to harmful substances If you have any doubt about a substance handle the substance as if it is potentially harmful...

Страница 31: ...ally safe manner that is consistent with local regulations Follow a regulated approved waste disposal program WARNING Self Ignition of Solvents Solvents with a self ignition temperature below 150 C mi...

Страница 32: ...on the chemical resistance of PEEK CAUTION Fused silica may be used in capillaries and tubes To avoid personal injury always wear safety glasses when handling fused silica tubing for example when cutt...

Страница 33: ...t s de toutes les substances que vous utilisez vitez l exposition des substances nocives Au moindre doute concernant une substance manipulez la comme s il s agissait d une substance potentiellement da...

Страница 34: ...la r glementation en vigueur au niveau local Suivez un programme d limination des d chets r glement et approuv AVERTISSEMENT Auto inflammation des solvants Les solvants poss dant une temp rature d aut...

Страница 35: ...ge d hexane d ac tate d thyle et de m thanol peuvent endommager le PEEK Ces acides peuvent cependant tre utilis s dans le cadre de proc dures de nettoyage condition que l exposition soit br ve Pour pl...

Страница 36: ...nts et les solvants non conducteurs par exemple l ac tonitrile pur Une d charge d nergie lectrostatique peut provoquer la formation d tincelles ce qui peut pr senter un risque d incendie vitez la g n...

Страница 37: ...e materials that are used in the flow path of the detector see the Specifications chapter For information about the materials that are used in the flow path of the other modules in the HPLC system ref...

Страница 38: ...details see section 11 1 page 248 Changes that you make to the device may void compliance with one or more of these EMC and safety standards Changes to the device include replacing a part or adding co...

Страница 39: ...3 Detector Overview Charged Aerosol Detectors Corona Veo RS Operating Manual Page 39 3 Detector Overview This chapter introduces you to the detector and the main components...

Страница 40: ...o mass spectrometry ionization of the analyte is not necessary Detection with great sub nanogram sensitivity and a wide dynamic range FocusJet nebulizer with concentric design for extended low pump fl...

Страница 41: ...mple The following picture shows the interior components of the detector and illustrates how the detector operates Figure 1 Operating principle of the detector No Description No Description 1 Mobile p...

Страница 42: ...er no 8 where they collide with a secondary stream of ionized gas no 9 that has passed through a corona charger no 10 Each dried aerosol particle undergoes surface diffusional charging where the level...

Страница 43: ...touch screen 2 Power LED 3 Leak tray drip tray 4 Drain ports for leak and waste 5 Leak sensor 6 Corona Veo RS only Stream switching valve The Corona Veo RS detector is equipped with a 6 port 2 positi...

Страница 44: ...mber Figure 3 FocusJet nebulizer 3 5 Gas Filter Assembly An assembly of two gas filters on the inner right side panel of the detector filters the supplied gas internally before it is used in the detec...

Страница 45: ...software the running sequence or batch is aborted If the Pump Off relay is connected to the pump the pump will stop mobile phase flow If not already turned on the drain pump is turned on automaticall...

Страница 46: ...graphy software such as the Chromeleon Chromatography Data System CDS The Chromeleon software provides complete instrument control data acquisition and data management TIP The charged aerosol detector...

Страница 47: ...4 Unpacking Charged Aerosol Detectors Corona Veo RS Operating Manual Page 47 4 Unpacking This chapter provides information for unpacking the detector and informs you about the scope of delivery...

Страница 48: ...pping insurance will compensate for the damage only if reported immediately Unpacking the Detector CAUTION Heavy Load Bulky Device The detector is too heavy or bulky for one person alone to handle saf...

Страница 49: ...placez pas ou ne levez pas le d tecteur par le panneau avant Cela risque d endommager le panneau avant ou le d tecteur Tools required Screwdriver Torx T20 Follow these steps 1 Place the shipping conta...

Страница 50: ...ectors Corona Veo RS Operating Manual 4 2 Scope of Delivery The following items are included in the delivery Detector with nebulizer Ship Kit For details about the kit content see section 10 2 Ship Ki...

Страница 51: ...d Aerosol Detectors Corona Veo RS Operating Manual Page 51 5 Installation This chapter specifies the requirements for the installation site and describes how to set up install and configure the detect...

Страница 52: ...ving it To lift or move the detector grasp the detector by the sides Do not move or lift the detector by the front bezel or white cover This will damage the bezel or the detector ATTENTION Charge lour...

Страница 53: ...ion 5 5 page 67 3 Set up the flow connections See section 5 6 page 81 4 Turn on the detector See section 5 7 page 98 Adjust the display brightness and date and time as required 5 Installation in the C...

Страница 54: ...s avec un autre syst me de gestion de donn es consultez la documentation du logiciel que vous utilisez et ou ex cutez la qualification manuellement Le manuel Instruments Installation Qualification Ope...

Страница 55: ...convenient access to the interior of each device in the system The workbench must stand in a secure and level position that is free of vibrations The bench top must be dry clean and resistant to chemi...

Страница 56: ...vice while the cover or panels are removed ATTENTION D charge lectrique ou endommagement de l instrument Le branchement de l appareil une tension sup rieure ou inf rieure celle sp cifi e pr sente un r...

Страница 57: ...sockets Operate the device only from a power outlet that has a protective ground connection In case of emergency it must be possible to reach the power cord easily at any time to disconnect the devic...

Страница 58: ...the electronics Therefore when using shipping or storing the device avoid or minimize conditions that can lead to a build up of condensation in the device For example avoid significant or fast changes...

Страница 59: ...tant for the performance of the detector Operate the detector in the specified humidity range with no condensation When the humidity is too high condensation may occur causing damage to the electronic...

Страница 60: ...n impair detector operation and lead to a decreased performance Avoid a vacuum or a negative pressure in the ventilation of the detector AVIS Un vide dans la ventilation peut provoquer une d pressuris...

Страница 61: ...les CAUTION Excessive Gas Supply Pressure An improper or excessive gas supply pressure can lead to an overpressure in the detector that can cause the safety valve in the detector to release gas In ext...

Страница 62: ...ur Ceci est particuli rement important lorsque vous raccordez des bouteilles de gaz pour la premi re fois et lors du remplacement des bouteilles de gaz Si la soupape de surpression lib re du gaz suite...

Страница 63: ...t le d bit de gaz du d tecteur sont teints avant de commencer remplacer le bloc de filtration de gaz Observez les exigences de lieu relatif l alimentation de gaz dans ce manuel NOTICE Gas Specificatio...

Страница 64: ...s substances non volatiles ceci peut provoquer une d t rioration des performances voire endommager le d tecteur Respectez les exigences et sp cifications relatives l alimentation de gaz donn es dans c...

Страница 65: ...may be a quick and easy source of nitrogen during installation However it is not recommended for routine operation The gas consumption of the detector is typically 4 L min The supply gas must be free...

Страница 66: ...nts in the detector remove the white cover on the right side of the front panel To allow easy access from the front the user accessible components and flow connections in the detector are located dire...

Страница 67: ...ith an UltiMate 3000 System If the detector is part of an UltiMate 3000 system for example for analytical HPLC applications stack the individual modules as shown below The system arrangement may vary...

Страница 68: ...ems If the charged aerosol detector is the only detector in the UltiMate 3000 system stack follow these steps 1 To position the charged aerosol detector grasp the detector by the sides in team effort...

Страница 69: ...tead 5 Rating plate indicating the serial number part number module name line and fuse rating and the manufacturer s address 6 USB Universal Serial Bus port B type connector Allows connection USB 1 1...

Страница 70: ...n power switch on off control 12 Functional grounding TIP Thermo Fisher Scientific recommends using the USB ports only as described above If the USB ports are used for any other purpose Thermo Fisher...

Страница 71: ...perature This may take several hours Wait until the condensation is completely gone before proceeding AVIS Assurez vous de l absence de condensation dans l appareil avant de brancher le d tecteur la l...

Страница 72: ...tem can be connected separately to the computer via the USB port on the rear panel of the respective module However Thermo Fisher Scientific recommends interconnecting all modules and then connecting...

Страница 73: ...ed from the computer or next USB hub by no more than 3 meters After connecting the USB cables and before turning on the power to a device for the first time verify that the chromatography software is...

Страница 74: ...sher Scientific recommends connecting all modules to the pump and then connecting the system to the computer via only one connection If the system includes a UV detector in addition to the charged aer...

Страница 75: ...rts a With the slotted screwdriver loosen the screw of the pin on the I O terminal to which you want to connect a wire b Insert the loose wire into the pin TIP Connect positive polarity negative polar...

Страница 76: ...c recommends that you always connect the Pump Off output to the pump within an HPLC system To use the Pump Off safety feature observe these guidelines for the pump The support relay on the pump must b...

Страница 77: ...he nebulizer tip is sharp and may be fragile Touching the nebulizer capillary can cause personal injury and damage to the capillary To avoid personal injury always wear safety glasses when handling th...

Страница 78: ...gas pressure certificate that is shipped with the nebulizer AVIS N buliseur sensible Le n buliseur pr sente une sensibilit lev e la contamination et l endommagement Respectez les consignes de s curit...

Страница 79: ...ection 5 3 page 55 2 Check the gas tubes Observe the following Use only the gas tubes that are shipped with the detector as well as additional or spare parts as recommended by Thermo Fisher Scientific...

Страница 80: ...to provide a good connection to the push in fitting on the gas inlet Slanted or angular cuts can lead to gas leaks TIP If you wish to use a different gas inlet tubing with metric dimensions use the i...

Страница 81: ...contenir des substances dangereuses Respectez les messages d avertissement et mentions de mise en garde figurant la section 2 3 reportez vous la page 23 NOTICE Before you connect the charged aerosol...

Страница 82: ...ctor use the capillary slots of the white front cover when the cover is installed Setting Up the Flow Connections To set up the flow connections and complete the installation of the detector follow th...

Страница 83: ...onal or spare capillaries and tubing as recommended by Thermo Fisher Scientific The connectors must be free from contaminants Even minute particles may cause damage to the system or lead to invalid te...

Страница 84: ...comes with the capillary To avoid damage to the capillary or connection tighten and loosen the Viper connections only when the system pressure is down to zero AVIS Serrez ou desserrez les capillaires...

Страница 85: ...ntional Fitting Systems Observe the following guidelines for conventional non Viper fitting systems When making a connection ensure that the capillary is fully inserted into the connection port and is...

Страница 86: ...or guide liquid leaks or waste liquids from the detector to the waste reservoir Figure 11 Drain ports No Description No Description 1 Leak port For liquid leaks from the internal leak tray left port 2...

Страница 87: ...fuites de liquide reporter une erreur et ou entra ner l inondation de l int rieur du d tecteur Utilisez des conduites d vacuation s par es une pour l orifice de fuite de liquide et une pour l orifice...

Страница 88: ...drain lines No Description No Description 1 Leak port drain line left port consisting of 2 Waste port drain line right port consisting of 1a L piece on the port 2a L piece on the port 1b Interconnect...

Страница 89: ...tee piece with the opening facing upward helps removing air from the drain system and thus prevents liquid from flowing back into the interior of the modules Both drain ports may be directed to the s...

Страница 90: ...ocate and unpack the in line filter 2 Open the filter cap of the filter assembly 3 Rinse the filter housing with deionized water 4 Install the filter cap and tighten it carefully until contact between...

Страница 91: ...e inlet capillary to the detector as follows Directly from the column or From the flow cell of a first detector such as a diode array detector in the HPLC system flow path series flow connection In a...

Страница 92: ...g valve Follow these steps Route and connect the capillary to the liquid flow inlet of the charged aerosol detector as required by the system arrangement See section 5 6 5 1 Connecting the Capillary f...

Страница 93: ...pillary connected to the detector here Corona Veo detector 4 After you have set up the capillary connections to the detector you can re install the white cover on the front panel Guide capillaries and...

Страница 94: ...let capillary to the charged aerosol detector 4 Connect the other end of the red capillary to the liquid flow inlet of the detector using a fitting This step depends as follows Corona Veo detector and...

Страница 95: ...nebulizer Keep the capillary connection as short as possible to minimize peak dispersion Observe all notes and specifications for flow cells of the first detector in the system from the Operating Man...

Страница 96: ...g valve connect ports no 2 3 and 4 of the valve The ports of the stream switching valve are assigned as follows Figure 15 Ports on the stream switching valve No Ports 2 Divert Waste Outlet to direct f...

Страница 97: ...1 On the stream switching valve connect the other end of the red inlet capillary to port 3 Inlet using a RheFlex fitting 2 Set up the connection between stream switching valve and nebulizer a Connect...

Страница 98: ...d on the data system computer When the power is turned on the required USB drivers are automatically found and the Windows operating system can detect the device 1 Turn on the detector with its main p...

Страница 99: ...When the detector has properly warmed up the display will show the Main Menu Figure 17 Start up screen left image and warm up screen right image 3 As required Adjust the brightness of the detector dis...

Страница 100: ...5 Installation Page 100 Charged Aerosol Detectors Corona Veo RS Operating Manual...

Страница 101: ...peration Charged Aerosol Detectors Corona Veo RS Operating Manual Page 101 6 Operation This chapter describes the elements for detector control provides information for routine operation and for shutd...

Страница 102: ...completed If this is not the case refer to the instructions in chapter 5 Installation before proceeding see page 51 For a description of the detector display see section 6 4 page 107 For a basic descr...

Страница 103: ...system always set the lower pressure limit for the pump This prevents damage resulting from leakage or from running the pump dry If there is evidence of leakage in the detector turn off the pump flow...

Страница 104: ...supply and ventilation in section 5 3 page 55 Observe the Specifications in chapter 9 page 235 French Version Veuillez prendre en consid ration les consignes de s curit suivantes lors de l utilisation...

Страница 105: ...d marrez le d bit de la pompe Pour interrompre le d bit de la pompe et le d bit de gaz du d tecteur Interrompez le d bit de la pompe en premier patientez au moins 5 minutes puis uniquement apr s cela...

Страница 106: ...romatography software Touch screen display with soft keys The soft keys allow you to operate the detector directly from the display See section 6 4 Touch Screen Display page 107 Status indicator The P...

Страница 107: ...table entry When you select an entry within the parenthesis additional options will become available TIP If the detector is connected to a chromatography software such as the Chromeleon software the s...

Страница 108: ...Date Time Setup Screen section 6 4 3 2 page 117 Setting date and time and service intervals for the gas filter and preventive maintenance Contacts Inputs Screen section 6 4 3 3 page 118 Activating out...

Страница 109: ...dedicated soft key If no errors or warnings are active the Status is Normal Figure 18 Main Menu screen example Soft key functions Soft key Description Bright Bright Increasing the display brightness...

Страница 110: ...n Menu To stop the Run Mode press the Exit soft key and on the next screen press the Continue to Exit soft key To navigate to screens from the Run Mode Menu use the dedicated soft keys To close screen...

Страница 111: ...will automatically actuate the valve Read only Nebulizer Range Only available if an analog output is installed on the analog output screen Setting the signal current range for the analog output of the...

Страница 112: ...izer gas pressure to the charging gas pressure low normal or high calibrated at factory Normal Ion Trap Voltage that is used to remove highly mobile gas ions 18 V 20 9 V Gas Pressure Indicates the inl...

Страница 113: ...status read only If no errors or warnings are active the Status is Normal Gain Displays the gain of output current for the graphical display Rate Indicates the display rate for the screen in seconds p...

Страница 114: ...erature reached depends on several factors including mobile phase composition liquid flow rate mobile phase temperature gas temperature and ambient temperature Setpoint Allows setting the evaporation...

Страница 115: ...the menu and screens To navigate to the System Setup Menu to the screens or return to the Main Menu use the dedicated soft keys Accessing screens to change detector parameters 1 Select the desired so...

Страница 116: ...age 116 SSV Only available with Corona Veo RS detectors Adjusting the position of the stream switching valve Nebulizer or Diverted Drain Checking the drain pump status and turning the drain pump off a...

Страница 117: ...nt Specifies the nebulizer gas pressure as specified on the certificate that was shipped with the nebulizer 40 65 0 psig 0 1 psig 276 448 kPa 2 8 4 5 bar Pressure Units Defines the default unit settin...

Страница 118: ...set next PM Date Displaying and resetting the next due date for preventive maintenance The interval is automatically set for 12 months after preventive maintenance The interval can be changed manually...

Страница 119: ...ase of an operating issue Certain problems in the charged aerosol detector cause an automatic stop of the pump flow to prevent a build up of excess liquid inside the detector Start TTL input Displayin...

Страница 120: ...cription Analog Board Setting the analog output board in the detector firmware as Installed or Not Installed TIP If an analog output board is installed on the screen the parameters Full Scale Range an...

Страница 121: ...see section 6 5 3 page 133 When the charged aerosol detector is connected in the system flow path Flush the detector only when the detector gas flow is turned on Deliver pump flow to the detector for...

Страница 122: ...le analysis See section 6 5 3 page 133 Verify that any air bubbles are completely flushed out of the system flow path 4 Turn on the detector gas flow and equilibrate the detector See section 6 5 4 pag...

Страница 123: ...de l azote avec le t trahydrofuranne ou d autres solvants hautement combustibles NOTICE Inappropriate or contaminated mobile phase can damage the detector The quality of the mobile phase significantly...

Страница 124: ...will damage the detector Do not use non volatile buffers AVIS Une exposition long terme du d tecteur des phases mobiles non volatiles comme des tampons inorganiques endommagerait le d tecteur N utilis...

Страница 125: ...se It is therefore recommended to only filter the aqueous buffer salt portion of a mobile phase TIP With solvent gradients non volatile impurities in the weaker solvent for example water in reversed p...

Страница 126: ...he intermixing of solvents from different reservoirs if applicable The mobile phase reservoirs should be clean borosilicate glass that is dedicated for use with volatile mobile phases In some applicat...

Страница 127: ...ormance Make sure that the mobile phase pH is within the allowed range of the detector 2 0 to 9 5 More importantly make sure that the mobile phase pH is well within the operating range of the LC colum...

Страница 128: ...g reagents such as triethylamine TEA TFA is known to be unstable after exposure to air Single use vials of TFA are therefore recommended if choosing this additive If using cationic ion pairing reagent...

Страница 129: ...peut entra ner des carts impr visibles de performance du n buliseur et du d tecteur Apr s installation du n buliseur r glez la pression de gaz sur le n buliseur sur la pression sp cifi e pour votre n...

Страница 130: ...urn to the Main Menu TIP If you operate the detector from a chromatography data system disconnect the detector to unlock the display functions and access the Main Menu 2 Navigate to the System Setup M...

Страница 131: ...se or decrease of the gas pressure on the detector display while turning the knob When the gas pressure setpoint matches the gas pressure from the nebulizer certificate continue with the next step Fig...

Страница 132: ...op the Run Mode and return to the Main Menu TIP If you operate the detector from a chromatography data system disconnect the detector to unlock the display functions and access the Main Menu 2 In the...

Страница 133: ...r until the system is free of any other liquid composition for example solvent from a previous run TIP If you use an online degasser in the system flush each channel of the online degasser before you...

Страница 134: ...ripple Check that the pump pressure reading is correct for the application and the ripple is within reasonable limits for the application 11 If the system includes a first detector in the flow path b...

Страница 135: ...z du d tecteur et ou de l alimentation de gaz Cette fuite de gaz peut pr senter un risque pour la sant et la s curit D marrez l alimentation de gaz et le d bit de gaz du d tecteur uniquement lorsque l...

Страница 136: ...patientez au moins 5 minutes puis uniquement apr s cela d marrez le d bit de la pompe Preparations 1 Make sure that you observe the site requirements for the gas supply See section 5 3 7 page 61 2 Tu...

Страница 137: ...or in section 6 5 1 page 123 The following table provides an overview of typical flow rates for certain column internal diameters Column Inner Diameter Typical Flow Rate 4 6 mm 1 0 mL min 3 0 mm 0 5 m...

Страница 138: ...nt de la limite de d bit endommagerait le d tecteur Starting Data Acquisition 1 To start data acquisition select the Run Mode soft key from the Main Menu screen 2 Equilibrate the detector See section...

Страница 139: ...ll divert liquid away from the detector in the event of an alarm condition If the detector is controlled from a chromatography software such as the Chromeleon software the valve can be actuated as par...

Страница 140: ...able temperature No air drafts No vibrations or mechanical shocks caused by external sources Stable backpressure and correct waste and leak drainage setup Use an on line degasser to degas the solvent...

Страница 141: ...pressure operating range columns may also be subject to column bleed Do not use a column that has been used with non volatile mobile phases Flush new columns to waste for several hours before you conn...

Страница 142: ...from the spray chamber The evaporation tube evaporates the more volatile components in the droplets to produce dried particles composed of non volatile analyte and background residue The efficiency of...

Страница 143: ...range that provides acceptable limits of sensitivity As a starting point use an evaporation temperature of 35 C Higher evaporation temperature settings can be used when analytes of interest have low...

Страница 144: ...from low to high temperature Select the most appropriate setting as starting point See the Guidelines for selecting the evaporation temperature above TIP Using performance metrics such as the precisi...

Страница 145: ...ase compositions For use with very low pump flow rates within the pump flow range allowed for the detector TIP The resulting nebulizer gas pressure will be below the gas pressure specified in the nebu...

Страница 146: ...and contaminants to a minimum Follow the Mobile Phase Guidelines for the Detector in section 6 5 1 page 123 Flush the system modules at regular intervals to remove any non volatile residues if applica...

Страница 147: ...ion rate for example 1 0 Hz This saves disk space and allows for a faster display of data in the Chromeleon software If any peaks of interest are less than a few seconds select a higher data collectio...

Страница 148: ...d documents provided with the software This manual assumes that the Chromeleon software is already installed on the data system computer and a valid license is available TIP In order to start the Chro...

Страница 149: ...ograms depending on the operating system Thermo Chromeleon 7 Instrument Configuration Manager Adding the charged aerosol detector to a System 1 If no system is set up yet On the Edit menu click Add In...

Страница 150: ...pending on the operating system Thermo Chromeleon 7 Services Manager Start Instrument Controller 2 Start the Chromeleon 7 client Click Start All Programs or Programs depending on the operating system...

Страница 151: ...l commands that are available for the system TIP The commands and parameters that are available in the Command window may vary depending on the user level in the Command window Normal Advanced or Expe...

Страница 152: ...sequence In a sequence you determine how the injections of a sample are analyzed and in which order they are processed Each injection of a sequence is processed by using an instrument method which de...

Страница 153: ...of the Console Starting the new sequence 1 On the Sequence Control Bar click Start 2 The sequence is appended to the queue and a Ready Check is performed If the Ready Check passes and if the instrume...

Страница 154: ...ail 4 On the panel tabset click the tab for a device 5 Use the controls for example buttons sliders to perform commands 6 If a function that you want to perform is not available on a panel press the F...

Страница 155: ...ow the samples are analyzed and in which order they are processed Each sample of a sequence is processed using a program file PGM file which defines the property values and timed control commands for...

Страница 156: ...Check passes and if the timebase is not currently running another sequence the sequence is started 6 8 3 Signal Channels in Chromeleon The following signal channels are available for the detector in...

Страница 157: ...r cannot collect raw data for the signal To change a signal name overwrite the existing name directly in the Name field 6 8 4 Chromeleon Audit Trail If the device firmware detects a problem the proble...

Страница 158: ...omeleon 7 or batch Chromeleon 6 8 can be started The current run is not interrupted Nevertheless Thermo Fisher Scientific recommends taking appropriate remedial action to resolve the problem Error The...

Страница 159: ...for a short period short term shutdown for example overnight observe these guidelines for the detector Check that sufficient gas is available to continue gas flowing through the detector This is to pr...

Страница 160: ...Afin d viter toute d t rioration du d tecteur d a rosols charg s respectez les consignes suivantes Vidangez toujours le d tecteur au moyen d un solvant pur ad quat avant d interrompre le fonctionneme...

Страница 161: ...ts in the detector are not miscible with water use an appropriate intermediate solvent Detector shall be transported or shipped after shutdown If no additive is used flush the system with isopropanol...

Страница 162: ...starting the Detector To restart the detector follow these steps 1 Prepare and restart the other modules in the system following the instructions in the Operating Manuals for the modules 2 Flush the c...

Страница 163: ...ance and Service Charged Aerosol Detectors Corona Veo RS Operating Manual Page 163 7 Maintenance and Service This chapter describes the routine maintenance and the service procedures that the user may...

Страница 164: ...vity referred to as Thermo Fisher Scientific service personnel Seul le personnel d entretien certifi par Thermo Fisher Scientific d sign par la suite par techniciens d entretien Thermo Fisher Scientif...

Страница 165: ...ltages are present inside the detector that could cause an electric shock Do not open the housing or remove protective panels unless specifically instructed to do so in this manual WARNING Escape of H...

Страница 166: ...ait until the system pressure is down to zero Unscrew the caps of the solvent reservoirs and remove the solvent lines together with the caps from the reservoirs Empty the solvents lines Refer to the O...

Страница 167: ...s raccordements fluidiques Les raccordements fluidiques et les capillaires peuvent contenir des substances potentiellement dangereuses pour la sant Il existe un risque de projection de solvant si des...

Страница 168: ...uites de solvant Resserrez le bouchon des r servoirs Resserrez le bouchon des r servoirs Consultez le Manuel d utilisation de la pompe Re serrez les capots de r servoirs AVIS D bit de gaz du d tecteur...

Страница 169: ...by step and use the tools recommended for the procedure Before opening the flow path to replace capillaries in the system turn off the pump flow and wait until the system pressure is down to zero Dir...

Страница 170: ...salt solutions flush the detector thoroughly after use with an appropriate solvent that does not contain buffers or salts The stability of water or highly aqueous 5 organic modifier mobile phase is h...

Страница 171: ...C system To maintain optimal analytical performance perform routine maintenance on each of the various HPLC system modules such as pump autosampler etc 7 4 2 Preventive Maintenance The preventive main...

Страница 172: ...nd other additives it is recommended to flush the detector daily using compatible solvents that do not contain additives Use the solvent with the best solubility characteristics for the sample matrix...

Страница 173: ...nation Decontamination is required for example when leakage or spillage has occurred or before service or transport of the detector Use a suitable cleaning detergent or disinfectant to ensure that the...

Страница 174: ...xcessive durant le processus de nettoyage Essuyez les composants nettoy s jusqu ce qu ils soient secs apr s nettoyage N utilisez pas le d tecteur tant qu il n est pas enti rement sec NOTICE Observe th...

Страница 175: ...re dans les composants fonctionnels du d tecteur Les liquides peuvent provoquer un court circuit en entrant en contact avec les composants lectroniques Preparations Turn off the power to the detector...

Страница 176: ...ION Fuite de gaz Du gaz peut s chapper des raccordements de gaz ouverts lors du d marrage du d bit de gaz du d tecteur et ou de l alimentation de gaz Cette fuite de gaz peut pr senter un risque pour l...

Страница 177: ...mobile phase to waste b Turn off the gas flow on the detector c Wait until the system pressure is down to zero before you continue d Turn off the gas supply to the detector 3 Turn off the detector wit...

Страница 178: ...n Analyses page 172 2 Turn off the pump flow and then the gas flow a Turn off the pump flow to the detector Wait at least 5 minutes During the waiting period the detector drains any remaining mobile p...

Страница 179: ...ire est fragile et ac r ceci peut provoquer un risque d accident corporel et d endommagement du capillaire Afin d viter de vous blesser rev tez toujours des lunettes de protection lorsque vous manipul...

Страница 180: ...orrectement raccord s et lorsque le capot de protection du bloc de filtration de gaz est install Parts and additional items required NOTICE The nebulizer is highly sensitive to contamination Even minu...

Страница 181: ...se to waste b Turn off the gas flow on the detector c Wait until the system pressure is down to zero before you continue d Turn off the gas supply to the detector 3 Turn off the detector with the main...

Страница 182: ...for the nebulizer 4 If the nebulizer is to be transported Pack the nebulizer a Carefully install the protective tubing to the nebulizer spray pipe Do not to touch the nebulizer tip with the protectiv...

Страница 183: ...person according to national regulations when the procedure is complete Further work in the enclosure must only be performed by Thermo Fisher Scientific service personnel AVERTISSEMENT Haute tension...

Страница 184: ...w are turned off Observe the Gas Supply Site Requirements in this manual ATTENTION Rupture de filtre gaz suite une pression d alimentation de gaz excessive Une pression d alimentation de gaz excessive...

Страница 185: ...stalled ATTENTION Fuite de gaz Du gaz peut s chapper des raccordements de gaz ouverts lors du d marrage du d bit de gaz du d tecteur et ou de l alimentation de gaz Cette fuite de gaz peut pr senter un...

Страница 186: ...is not placed in the bottom position in the system stack Stop the detector operation and remove the detector from the system stack See section 7 12 Removing the Detector from the System Stack page 20...

Страница 187: ...rection arrows on the gas filters before you continue The incoming gas enters the bottom charcoal filter then the top HEPA filter and exits off to the gas cycle inside the detector AVIS Les raccordeme...

Страница 188: ...ilter assembly push in the locking ring on each elbow fitting with the multitool no 1 in Figure 37 Leave the elbow fittings connected to the gas filter assembly b Carefully pull the gas tubes off from...

Страница 189: ...6 Push the new gas filter assembly into the clamps observing the orientation signs for the gas flow on the gas filters Figure 39 Correct installation of the gas filter assembly No Description No Desc...

Страница 190: ...right side panel Position the side panel on the right of the detector Make sure that the screws match the recesses 9 With the screwdriver tighten the 3 attachment screws 10 Have an electrical safety...

Страница 191: ...et Filter Chg Date softkey to reset the gas filter replacement interval for 12 months 15 Turn on the gas flow to check for proper functioning of the gas filters See section 6 5 4 1 Turning On the Dete...

Страница 192: ...or recommendations on flushing the detector see section 7 4 3 Flushing the Detector between Analyses page 172 2 Turn off the pump flow and then the gas flow a Turn off the pump flow to the detector Wa...

Страница 193: ...tator from the valve body To ensure that the sealing surface of the stator cap is not damaged place the stator on its outer face 3 Carefully remove the rotor seal with your hand or a small screwdriver...

Страница 194: ...oroughly with the microfiber cloth Take care that no surfaces are scratched while you are cleaning the components After cleaning it is not necessary to dry the rotor 3 Reassemble the valve See section...

Страница 195: ...nt Figure 43 Reassembling rotor and stator 2 Position the stator on the valve body Make sure that the stator is in correct orientation 3 Tighten the 2 screws that attach the stator to the valve gently...

Страница 196: ...om both the power source and the device Use only the fuses of the type and current rating specified for the detector by Thermo Fisher Scientific Do not use repaired fuses and do not short circuit the...

Страница 197: ...Description 1 2 3 Main power switch on off control Power inlet connector Fuse holder cartridge 1 Use the screwdriver to remove the fuse holder 2 Replace the two fuses with new fuses of the specified t...

Страница 198: ...lease as appropriate TIP When a new firmware version is released the new version will be included in the next available Chromeleon Service Release The new firmware will not be transferred automaticall...

Страница 199: ...t la proc dure Au d but de la proc dure de mise jour un message affiche la version du microprogramme install e sur le d tecteur et la version transf rer depuis le logiciel Chromeleon Si la version du...

Страница 200: ...d tecteur est trop lourd ou encombrant pour tre soulev en toute s curit par une seule personne Afin d viter toute blessure corporelle ou d t rioration du d tecteur veuillez respecter les consignes su...

Страница 201: ...Disconnect the power cord from the detector and power source 5 Disconnect all cables and capillaries to other devices 6 Disconnect the gas and drain tubes a Disconnect the gas inlet and exhaust tubes...

Страница 202: ...ing the detector into the system stack or when removing it To lift or move the detector grasp the detector by the sides Do not move or lift the detector by the front bezel or white cover This will dam...

Страница 203: ...ts main power switch and disconnect the power cord 3 Remove all cables and flow connections to other devices 4 Remove the detector from the system stack See section 7 12 Removing the Detector from the...

Страница 204: ...nal shipping container is not available appropriate containers and packing material can be ordered from the Thermo Fisher Scientific sales organization 2 If you need to return the detector to Thermo F...

Страница 205: ...her refuse d accepter des instruments pour la r paration dont le certificat de d contamination n est pas fourni avec l instrument Restarting the Detector after Shipping To restart the detector after s...

Страница 206: ...7 Maintenance and Service Page 206 Charged Aerosol Detectors Corona Veo RS Operating Manual...

Страница 207: ...8 Troubleshooting Charged Aerosol Detectors Corona Veo RS Operating Manual Page 207 8 Troubleshooting This chapter is a guide to troubleshooting issues that may arise during operation of the detector...

Страница 208: ...tion have the serial number and technical name available when communicating with Thermo Fisher Scientific Status Indicator on the Detector Display The detector display provides an overview of the dete...

Страница 209: ...ta system the problem is also reported to the software and a message appears in the audit trail of the software In case of Chromeleon a related message for the problem appears in the Chromeleon Audit...

Страница 210: ...or Codes page 214 If the detector does not power up a Check the power cord and make sure that it is properly connected to the power inlet on the detector and the power source b Replace the fuses See s...

Страница 211: ...ectly Other components in the system Check that the other components in the system are connected properly and operate properly according to the instructions for each component Routine and preventive m...

Страница 212: ...splays the Main Menu 2 Follow the remedial actions for the respective self test error code After each remedial action turn the detector off and on to perform self test diagnostics and check if the rem...

Страница 213: ...liquid to flow back into the detector Resolve the flooding See section 8 5 3 page 224 Repeat the self test If the problem persists contact Technical Support 100 An error occurred with the ion trap su...

Страница 214: ...ates that a warning is active Certain soft key functions become available Pressing the Mute Beep soft key turns off the beep for the current alarm Pressing the Continue soft key before the problem is...

Страница 215: ...source for the leakage see section 8 5 1 page 220 15011 High engine temperature The internal temperature of the engine is too high Turn the detector off and on see top line of the table If the voltag...

Страница 216: ...he current alarm Pressing the Continue soft key before the problem is resolved bypasses the error warning dialog and shows the Main Menu If the detector is operated from a chromatography data system s...

Страница 217: ...igh volatility or with low flow rates Resolve the flooding See section 8 5 3 page 224 29002 Low flow ratio The gas flow ratio is below the specified range for more than 60 seconds The following action...

Страница 218: ...is available on the Diagnostics screen If the error persists contact Technical Support 29004 High gas pressure The nebulizer gas pressure has exceeded the maximum limit The following actions occur The...

Страница 219: ...let tubing and gas filter assembly for signs of gas leakage and proper connection to the detector Turn on gas flow and check for any unusual noise Turn the detector off and on Check the self test resu...

Страница 220: ...ral rules for maintenance and service as presented in chapter 7 Maintenance and Service page 163 Follow these steps 1 Turn off the pump flow and then the gas flow a Turn off the pump flow to the detec...

Страница 221: ...f leakage are present proceed with the steps below Corona Veo RS only Stream switching valve If liquid is visible on the stream switching valve leakage may have occurred on the capillary connections o...

Страница 222: ...in the Resolving Gas Supply Overpressure section in this manual ATTENTION Pression d alimentation de gaz excessive Une pression d alimentation de gaz inappropri e ou excessive peut conduire une surpre...

Страница 223: ...ains any remaining mobile phase to waste b Turn off the gas flow on the detector c Wait until the system pressure is down to zero before you continue d Turn off the gas supply to the detector 2 On the...

Страница 224: ...a chromatography software the running sequence or batch is aborted If not already turned on the drain pump is turned on automatically If the detector is connected to a LC pump using the Pump Off outp...

Страница 225: ...tor in an HPLC system Locate the table for the type of symptom you have find the possible cause and use the description of the solution to help you solve your problem quickly Also check the detector d...

Страница 226: ...n temperature and or less volatile solvent such as 100 water is used Operate the detector only within the allowed flow rate range If using a post column make up flow make sure that the combined rate f...

Страница 227: ...oise Air trapped in the system Purge the system as necessary refer to Pump Operating Manual Ambient temperature fluctuations Check the thermostat in the laboratory If possible note the temperature flu...

Страница 228: ...rd or sample is soluble in the mobile phase Use diluted sample or standard if necessary Nebulizer nozzle capillary clogged Poor solubility of analyte during nebulization analyte build up Check the bac...

Страница 229: ...nated Clean or replace the column Reduce the injection volume or injection mass Eluent has changed Use freshly prepared solvent Use HPLC grade eluents only Extra column volume too large If early peaks...

Страница 230: ...e gas leak and or replace the gas tubes see section 7 5 page 176 Leaking liquid at the detector inlet Check the capillary connections Check the tubing that is connected to the waste port of the detect...

Страница 231: ...sample in the autosampler if possible Unstable environmental conditions Make sure that the temperature and air humidity are constant Use column thermostatting Avoid draft Injection volume variation O...

Страница 232: ...cient Use freshly prepared solvent Observe the Mobile Phase Guidelines for the Detector in section 6 5 1 page 123 Negative peaks Sample and mobile phase differ in composition Make sure that the sample...

Страница 233: ...exhaust Flooding inside the detector pump flow turned on while no gas flow present Flooding can occur if the detector is turned off while liquid is still flowing into the detector See section 8 5 3 R...

Страница 234: ...8 Troubleshooting Page 234 Charged Aerosol Detectors Corona Veo RS Operating Manual...

Страница 235: ...d Aerosol Detectors Corona Veo RS Operating Manual Page 235 9 Specifications This chapter provides the physical and performance specifications including information about the materials used in the flo...

Страница 236: ...ments 0 1 0 2 0 5 1 0 2 0 3 6 5 0 10 0 seconds Digital noise filtering 4 th order low pass Bessel filter Warm up time 30 minutes to 35 C evaporation temperature Integrated stream switching valve Coron...

Страница 237: ...ition for Corona Veo RS only PTFE Valcon H NOTICE For information about the chemical resistance of materials refer to the technical literature Solvent and additive information See section 2 4 page 37...

Страница 238: ...e Specification Range of use Indoor use only Ambient temperature 15 35 C Ambient humidity 12 80 relative humidity non condensing Pollution degree 2 Power requirements 100 240 V AC 50 60 Hz 100 VA Over...

Страница 239: ...ating Manual Page 239 10 Accessories Consumables and Replacement Parts This chapter describes the standard accessories that are shipped with the detector and the accessories that are available as an o...

Страница 240: ...with the replacement parts and additional components options and peripherals specifically authorized and qualified by Thermo Fisher Scientific Accessories consumables and replacement parts are always...

Страница 241: ...tor drainage components for leak port and waste port Tee pieces 2 L pieces 4 Flexible hose 11 4 mm x 8 3 mm O D x I D 2 m length 1 Tubing kit including 1 Gas inlet tubing 1 8 x 1 4 I D x O D 2 5 m len...

Страница 242: ...ess steel 1 4 1 Signal synchronization cable for connection to LPG 3400XRS pump 1 Signal cable 6 pin miniDIN length 5 m 1 10 2 2 Corona Veo Detector Item Quantity in shipment Detector drainage compone...

Страница 243: ...n socket wrench 1 2 x 9 16 Slotted screwdriver 2 5 x 50 mm 1 Capillary Viper 0 13 mm I D 350 mm length For connection to an optical detector for example in an UltiMate 3000 system 1 In line filter sta...

Страница 244: ...Corona air compressor 230 V 6295 0300 Supplies the required amount of air pressure for operation of the detector Corona nitrogen generator 1010 6295 0200 Provides on demand uninterrupted supply of dry...

Страница 245: ...porosity 0 5 m 10 frits 70 4539 Fitting one piece hand tight 10 fittings 2200 5503 In line filter stainless steel with filter frit included 70 4538 RheFlex fittings PEEK 1 16 finger tight 6000 0012 Vi...

Страница 246: ...ewdriver 2 5 x 50 mm 6081 9190 Tubing cutter 1 8 x 3 4 70 7112 Power cords Description Part No Power cord Australia 6000 1060 Power cord China 6000 1080 Power cord Denmark 6000 1070 Power cord EU 6000...

Страница 247: ...endix Charged Aerosol Detectors Corona Veo RS Operating Manual Page 247 11 Appendix This chapter provides additional information about compliance the use of the digital I O ports and internal gas flow...

Страница 248: ...Directive on the restriction of the use of certain hazardous substances in electrical and electronic equipment The CE mark on the device indicates that the product is compliant with the directive Chin...

Страница 249: ...quage CE appos sur l appareil atteste de la conformit du produit la directive R glementation RoHS chinoise Mesures de contr le de la pollution provenant de produits d information lectroniques S il y a...

Страница 250: ...er State and these companies should dispose of or recycle this product For further information contact Thermo Fisher Scientific French Version Ce produit doit tre conforme la directive 2002 96 CE de l...

Страница 251: ...terference at his expense French Version Cet quipement a t test et d clar conforme aux limites pour un appareil num rique de classe A conform ment la partie 15 du r glement de la FCC Commission f d ra...

Страница 252: ...output Positive polarity 5 CC2 Relay output Negative polarity 6 GND Ground 7 Divert TTL input Positive polarity 8 Divert TTL input Negative polarity 9 GND Ground Digital I O Terminal B Pin Signal Name...

Страница 253: ...e following Voltage must be between 0 V and 5 V The polarity sense of the device must match that of the detector The positive and negative polarities of the device must be connected to the correspondi...

Страница 254: ...rity of the output to which it belongs Pump Off The Pump Off output contact is used to send a signal to the pump or other external device to stop the flow of mobile phase and turn off the pump This si...

Страница 255: ...Charged Aerosol Detectors Corona Veo RS Operating Manual Page 255 11 3 Internal Gas Flow Path Diagram The following diagram shows the gas and aerosol flow paths inside the detector Figure 46 Gas flow...

Страница 256: ...11 Appendix Page 256 Charged Aerosol Detectors Corona Veo RS Operating Manual...

Страница 257: ...12 Index Charged Aerosol Detectors Corona Veo RS Operating Manual Page 257 12 Index...

Страница 258: ...tector 12 connectors 69 consumables 239 245 Contacts and Inputs display 118 control elements 106 cTUVus mark 248 D data collection rate 146 Date Time Setup display 117 decontamination 173 detector gas...

Страница 259: ...nnection terminal 69 connect 74 pin assignment 252 relay outputs 254 TTL inputs 253 in line filter 90 installation 51 interior front components 43 L leak detection 45 leak port 86 leak sensor 45 220 l...

Страница 260: ...kit 241 short term shutdown 159 shutdown long term 160 short term 159 signal channel 156 CAD_1 156 evaporation tube temperature 157 gas regulator pressure 156 signal words 18 site requirements 55 sof...

Страница 261: ...12 Index Charged Aerosol Detectors Corona Veo RS Operating Manual Page 261...

Страница 262: ...Thermo Fisher Scientific Inc 168 Third Avenue Waltham Massachusetts 02451 USA www thermofisher com...

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