Thermo Scientific Corona Veo, Руководство по эксплуатации

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6 • Operation
Page 126 Charged Aerosol Detectors Corona Veo (RS) Operating Manual
• If the detector is inadvertently exposed to a non-volatile mobile
phase, use water or appropriate solvent with no additives to remove
the salts from the detector.
Typical compatible solvents for use with the detector
• Water
•
Methanol
• Isopropanol
•
Acetonitrile
• Acetone
•
Methylene chloride
•
Hexane
•
Chloroform
•
Tetrahydrofuran
NOTE: Use THF with nitrogen gas only.
6.5.1.3
Mobile Phase Delivery System
• The pump should deliver continuous flow and at the same time
ensure the intermixing of solvents from different reservoirs, if
applicable.
•
The mobile phase reservoirs should be clean borosilicate glass that is
dedicated for use with volatile mobile phases.
In some applications, however, it may be necessary to use plastic
reservoirs, for example when using extreme pH aqueous eluents
(such as > pH 12).
•
Consider the pump flow rate limit of the detector when preparing
analysis. Operate the detector only within the allowed pump flow
rate range.
•
It is recommended to use online degassers for HPLC systems with
the detector. Make sure to thoroughly flush any degasser channel
that has been exposed to non-volatile buffers. In some cases, it may
be necessary to dedicate degasser channels to only use volatile
mobile phases.