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A-10 Operator’s Manual – OPTI CCA-TS
APPENDIX A - TECHNICAL SPECIFICATIONS
BE
(act)
Base excess at actual oxygen saturation.
( ) ( ) ( )
[ ]





 −
⋅ ⋅ −
+ − − ⋅ + ⋅ ⋅ ⋅
−
100
O
1 tHb 2 . 0
HCO 26 . 24 4 . 7 pH 5 . 9 tHb 63 . 1 tHb 0.0143 - 1 = BE
2
3 (act)
S
[mmol/L ]
8
BB
The buffer base is the concentration of buffering anions which is available in whole blood to
buffer strong acids and consists mainly of protein anions and bicarbonate. Of the protein anions,
hemoglobin is the most significant.
tHb 42 . 0 + 7 . 41 + BE = BB ⋅
[mmol/L]
6
SO
2
(c)
The oxygen-hemoglobin dissociation curve theoretically allows that oxygen saturation of
available hemoglobin can be calculated, provided the form of the curve is known. Factors
which are known to affect this curve include: hemoglobin species, pH, P CO
2
, temperature and
2,3 diphosphoglycerate (2,3 DPG) content. Although it is possible to calculate this value, the
assumptions which are made in the calculation can cause significant errors in the resulting value
for those patients who are in the most critical clinical state. The OPTI CCA-TS has the capability
to provide a measured S O
2
from the blood sample. It is recommended that this measured value, if
available, should be used in preference to the calculated S O
2.
If not available from measurement, and if calculation is selected:
5 . 21
BE 0.0013 + )
26.7
21.5
lg( - 7.4) - (pH 0.48 O lg O lg
4.113 10 1.3632 O lg 2.9 = lgQ
: Fetal
26.7
BE 0.0013 + )
26.7
26.7
lg( - 7.4) - (pH 0.48 O lg O lg
4.172 10 1.661 O lg 2.9 = lgQ
: Adult
100%
1 + Q
Q
% SO
50
2
k
2
O 0.0533
k
2
50
2
k
2
O 0.074
k
2
2
k
2
k
2
=
⋅ ⋅ + =
− ⋅ + ⋅
=
⋅ ⋅ + =
− ⋅ + ⋅
⋅ =
⋅ −
⋅ −
P
P P
P
P
P P
P
P
P
8 Zander R., Die korrekte Bestimmung des Base Excess (BE mmol/l) im Blut. Anesthesiol. Intensivmed. Notfallmed.
Schmerzther.
(7)
(6)