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Operator’s Manual – OPTI CCA-TS PCO2-1
ANALYTES
P
CO
2
PCO
2
Clinical Significance
1
The P CO
2
value of arterial blood is used to assess how well the body eliminates carbon dioxide, a
by-product of metabolism. A P CO
2
value below the normal range is termed respiratory alkalosis and
indicates
hypocapnia
, a condition caused by increased alveolar ventilation such as hyperventilation.
An arterial
P
CO
2
above the normal range is termed respiratory acidosis and indicates hypercapnia , a sign
of ventilatory hypoventilation and failure, resulting from cardiac arrest, chronic obstructive lung disease,
drug overdose, or chronic metabolic acid-base disturbances.
Measurement Principle
The P CO
2
optode measurement principle is based upon placing a pH optode behind an ion-
impermeable membrane 2, just as conventional P CO
2
blood gas electrodes employ the Severinghaus CO
2
electrode construction. As such, P CO
2
optodes may suffer interference from volatile acids and bases in
blood, just as conventional P CO
2
electrodes.
The
P
CO
2
partial pressure is influenced by the local barometric pressure, as dictated by Dalton’s law.
The OPTI CCA-TS incorporates a pressure transducer, which accurately tracks the local barometric
pressure and automatically compensates for it. The OPTI CCA-TS has been factory-calibrated to the
absolute barometric pressure.
Measurement Range
Range Resolution (Low/High) Units
10 to 200 1/0.1 mmHg
Standard Reference Cassette (SRC) Limit Values
LOW NORMAL HIGH Units
70.0 ± 2 40.0 ± 2 20.0 ± 2 mmHg