OPTIMedical OPTI CCA-TS, Руководство оператора, Страница: 208 / 271

K-2 Operator’s Manual – OPTI CCA-TS
POTASSIUM
ANALYTES
Interferences
The OPTI CCA-TS K
+
sensor has no measurable interference from Na
+
variation within the range 100-
190 mmol/L.
The OPTI CCA-TS K
+
results include an appropriate correction for pH at all values of pH.
This correction may introduce an extra source of variability at the extreme values.
The OPTI CCA-TS K
+
sensor has no interference from ammonia or ammonium ion present at normal
physiologic levels (below 100 µ mol/L). At hyperammonemia (plasma levels of 300 µ mol/L),
the OPTI CCA-TS K
+
sensor will show a potassium offset of +0.4 mmol/L, and at extreme
hyperammonemia (plasma levels of 3000 µ mol/L), the OPTI CCA-TS K
+
sensor will show a potassium
offset of +4.4 mmol/L.
Heparin salts are the only acceptable anticoagulants. Other anticoagulants such as citrate, EDTA, oxalate,
and fluoride cause significant interferences to the electrolyte sensors.
The following exogenous interferents were quantified in tonometered plasma, showing interferences to
dyes which typically have short half-lives within the body before being metabolized by the liver.
Substance amount K
+
change (mmol/L)
Sodium fluorescein 26 mg/dL -0.7
Cardio (indocyanine) green 0.5 mg/dL -0.4
Methylene blue 25 mg/dL +2.4
Only clear, uncolored quality control materials, such as OPTI CHECK or OPTI CHECK PLUS
brand aqueous controls should be used with the OPTI CCA-TS system. Colored materials,
including proficiency testing materials, may interfere with the ion measurement, or fail to be
properly aspirated.
Reproducibility
Typical Within-Run ( Swr ), Between-Day ( Sdd ) and Total ( ST ) Precision is determined from 1 run per
day with 2 replicates per run for 20 days on each of two OPTI CCA instruments. Potassium values are
expressed in mmol/L.
Material mean S
wr (CV%)
S
dd (CV%)
S
T (CV%)
OPTI CHECK PLUS
(aqueous control solution)
Level 1 2.61 0.004 (0.2) 0.026 (1.0) 0.026 (1.0)
Level 2 4.50 0.005 (0.1) 0.030 (0.7) 0.030 (0.7)
Level 3 5.58 0.006 (0.1) 0.048 (0.9) 0.47 (0.4)
Serum 7.11 0.010 (0.1) 0.08 (1.1) 0.08 (1.1)
Reduced Bovine Hemoglobin 2.92 0.004 (0.1) 0.02 (0.8) 0.02 (0.8)
Solution