Waters Xevo TQD, Overview And Maintenance Manual

Page: 74 / 250

3 Changing the Mode of Operation
74 March 14, 2014, 715004387 Rev. B
A light within the source provides illumination for the spray, which you can
observe using the microscope camera mounted on the corner of the source
housing.
The low flow rates involved with operating the NanoFlow source prohibit its
use with the instrument’s solvent delivery system.
Installing the NanoFlow source
Required material
Chemical-resistant, powder-free gloves
To install the NanoFlow source:
1. Prepare the instrument for working on the source (see page 88 ) .
2. Remove the probe from the currently installed source.
• If you are removing an ESI probe, see page 61 .
• If you are removing an IonSABRE II probe, see page 65 .
3. Remove the existing source enclosure (see page 90 ).
Warning:
To avoid personal contamination with biohazards or
toxic materials, and to avoid spreading contamination to
uncontaminated surfaces, wear clean, chemical-resistant,
powder-free gloves while performing this procedure. The source
components can be contaminated.
Warning:
To avoid electric shock, ensure that the instrument is
prepared for working on the source before commencing this
procedure.
Warning:
To avoid burn injuries, ensure that the source heater is
turned off and the block is cool before opening the source. The ion
block, which can be hot, is exposed when you fit the NanoFlow
source.
Warning:
To avoid burn injuries, take great care while working
with the probe and source; these components can be hot.