MS/MS operating modes
March 14, 2014, 715004387 Rev. B
39
Product (daughter) ion mode
Product ion mode is the most commonly used MS/MS operating mode. You can
specify an ion of interest for fragmentation in the collision cell, thus yielding
structural information.
Product ion mode:
Typical applications
Product ion mode is typically used for the following applications:
•
Method development for MRM screening studies:
–
Identifying product ions for use in MRM transitions.
–
Optimizing CID tuning conditions to maximize the yield of a specific
product ion to be used in MRM analysis.
•
Structural elucidation (for example, peptide sequencing)
MS1
Static (at precursor mass)
MS2
Scanning
Collision cell
Fragmenting
precursor ions and
passing all masses
Summary of Contents for Xevo TQD
Page 2: ...ii March 14 2014 715004387 Rev B...
Page 22: ...xxii March 14 2014 715004387 Rev B...
Page 56: ...2 Preparing for Operation 56 March 14 2014 715004387 Rev B...
Page 200: ...4 Maintenance Procedures 200 March 14 2014 715004387 Rev B...
Page 216: ...A Safety Advisories 216 March 14 2014 715004387 Rev B...
Page 242: ...B External Connections 242 March 14 2014 715004387 Rev B...
Page 246: ...C Materials of Construction and Compliant Solvents 246 March 14 2014 715004387 Rev B...
