Combined APPI/APCI source
March 14, 2014, 715004387 Rev. B
67
APCI operation
The atmospheric pressure chemical ionization (APCI) mode produces singly
charged protonated or deprotonated molecules for a large range of nonvolatile
analytes. In APCI mode, the source is fitted with an APCI corona pin. Unused,
the APPI lamp drive assembly is retracted from the source.
APCI mode:
The IonSABRE II probe introduces vaporized sample into the source. The
sample passes between the sample cone and the corona pin, which typically
operates with a discharge current of 5
µA. The corona discharge generates
ions that react with the mobile phase molecules to produce stable reagent
ions. Analyte molecules in the mobile phase react with the reagent ions at
atmospheric pressure and become protonated (in the positive ion mode) or
deprotonated (in the negative ion mode). The sample and reagent ions pass
through the sample cone.
IonSABRE II probe
Retracted APPI lamp drive
assembly
Sample cone
APCI corona pin
Summary of Contents for Xevo TQD
Page 2: ...ii March 14 2014 715004387 Rev B...
Page 22: ...xxii March 14 2014 715004387 Rev B...
Page 56: ...2 Preparing for Operation 56 March 14 2014 715004387 Rev B...
Page 200: ...4 Maintenance Procedures 200 March 14 2014 715004387 Rev B...
Page 216: ...A Safety Advisories 216 March 14 2014 715004387 Rev B...
Page 242: ...B External Connections 242 March 14 2014 715004387 Rev B...
Page 246: ...C Materials of Construction and Compliant Solvents 246 March 14 2014 715004387 Rev B...
