PROPRIETARY INFORMATION
CONFIDENTIAL MATERIAL
Assays/Reagents
Not for Customer Distribution
112
AEROSET
®
System Troubleshooting Guide
94816-107—November 2004
Benzodiazepines
Cross Reactivity Testing Performed on the AEROSET System by SYVA
Compounds listed in the following table yielded a result
approximately equivalent to the Multi DOA Cutoff calibrator
(200 ng/mL lormetazepam).
Compounds listed in the following table yielded a negative
result at 200 ng/mL lormetazepam (Multi DOA Cutoff
calibrator) when tested at the concentration listed.
Compound
Concentration
Calculated ng/mL
SYVA Package Insert
ng/mL
7-aminoflunitrazepam
341
295
Compound
SYVA Package Insert
µg/mL (Tested at
150 ng/mL Cutoff)
Acetaminophen
1,000
N
-Acetylprocainamide (NAPA)
400
Acetylsalicylic acid
1,000
Alpha-acetyl-
N
,
N
-dinormethadol
(dinor LAAM)
25
l
-Alpha-acetylmethodol (LAAM)
25
Amitriptyline
1,000
Buprenorphine
100
Caffeine
1,000
Cimetidine
1,000
Clomipramine
2.5
Clonidine
1,000
Codeine
500
Cotinine
100
Cyclobenzaprine
28
Desipramine
800
Diphenhydramine
1,000
Doxepin
10
2-Ethylidene-1,5-dimethyl-3,
3-diphenylpyrrolidine (EDDP)
1,000