Micromass Quattro Ultima, User Manual

Page: 15 / 227

Instrument Description
Overview
The Micromass Quattro Ultima is a high performance benchtop triple quadrupole mass
spectrometer designed for routine LC-MS-MS operation. Quattro Ultima may be
coupled to:
•
a HPLC system with or without an autosampler.
•
an infusion pump.
•
a syringe pump.
Ionisation takes place in the source at atmospheric pressure. These ions are sampled
through a series of orifices into the first quadrupole where they are filtered according
to their mass to charge ratio (
m
).
The mass separated ions then pass into the hexapole collision cell where they either
undergo collision induced decomposition (CID) or pass unhindered to the second
quadrupole. The fragment ions are then mass analysed by the second quadrupole.
Finally the transmitted ions are detected by a conversion dynode, phosphor and
photomultiplier detection system. The output signal is amplified, digitised and
presented to the data system.
Instrument Description
Page 15
Quattro Ultima
User's Guide
Samples
from the liquid
introduction system
are introduced at
atmospheric pressure into the
ionisation source.
Ions are sampled through a series of orifices.
The ions are filtered according to their mass to charge
ratio (
).
The mass separated ions undergo collision induced decomposition.
The fragment ions are filtered according to their mass to charge ratio.
The transmitted ions are detected by the photomultiplier detection system.
The signal is amplified, digitised and presented to the MassLynx NT™ data system.
m
MassLynx NT
Data System
Sample Inlet
Sampling Cone
and Ion Block
Ion Tunnels
Prefilter 1
Quadrupole 1
Collision Cell
Prefilter 2
Quadrupole 2
Detector