6
Method Parameters
Set the 2D-LC Method parameters
2D-LC User Guide
140
Use Loop Flushing and Active Solvent Modulation (ASM)
If your 2D-LC instrument is equipped with the G4236A 2D-LC ASM Valve, this
method development feature helps finding the optimal dilution of
1
D solvents in
the sample loop. ASM leads to best
2
D resolution at lowest cycle time.
ASM settings of 2D-LC method parameters allow switching on and off the use of
the ASM functionality.
•
If this option is off, it works as a standard 2D-LC valve without dilution.
•
If this option is on, the user can set how often he wants to flush the sample
loop during the ASM phase.
1
To use ASM, mark the
ASM
check box.
This action activates the Active Solvent Modulation.
The
ASM Factor
is a read-only value and cannot be changed.
NOTE
For visual verification of the ASM phase, you can check the Analytical Gradient
Graph. There you can see the impact of the ASM phase before the
2
D run starts.
The gradient with ASM increases the cycle/modulation time.
NOTE
To change the ASM factor you must install and configure the new ASM capillary
in the 2D-LC UI, see
“2D-LC Capillaries Configuration Tool”
There are four different ASM capillaries available. You can find more info for
Installation and Configure of different ASM capillaries for optimizing the results,
see
Содержание 1290 Infinity II 2D-LC Solution
Страница 122: ...5 2D LC Data Acquisition in MassHunter Workstation 11 Instrument Details 2D LC User Guide 122 3 Click Screen 4 Click OK...
Страница 263: ...2D LC User Guide 263 9 Data Analysis GC Image Basic Information 3 Import parameters...
Страница 264: ...9 Data Analysis GC Image Basic Information 2D LC User Guide 264 4 Fit view...
Страница 267: ...2D LC User Guide 267 9 Data Analysis GC Image Basic Information 11 View single 2D chromatograms 12 Select blobs...