GE AKTApure, User Manual, Page: 368 / 522

Possible cause and action Problem
• This error can only occur when the temperature compensation
is turned on. The error will occur when the temperature is
outside the range 2°C to 40°C.
Make sure the temperature of the calibration solution is within
2°C and 40°C.
Temperature out of range
for calibration
• Air in the Conductivity flow cell
Use the Flow restrictor.
Remove the air by flushing the flow cell with water or buffer.
• Leaking tubing connections
Tighten the connectors. If necessary, replace the connectors.
• Unclean Conductivity flow cell
Clean the Conductivity flow cell. See Section 7.6.10 Clean the
Conductivity flow cell, on page 300.
• Poor mixing function
Check the Mixer chamber size and change chamber if necessary,
see Select Mixer chamber, on page 152.
Check the motor operation of the Mixer. Place a magnet close to
the Mixer chamber during run. The magnet should vibrate.
Check that the Mixer chamber is free from solids. To replace the
inline filter, see Section 7.3.2 Replace the inline filter, on page 266.
Baseline drift of noisy signal
• Unclean conductivity flow cell
Clean the Conductivity cell, see Section 7.6.10 Clean the Conduc-
tivity flow cell, on page 300.
• The ambient temperature may have decreased/increased
Use a temperature compensation factor. The temperature com-
pensation factor is found in System Control:System Settings:Con-
ductivity. Instruction regarding the factor is also found in Sec-
tion 7.7.3 Calibrate the Conductivity monitor, on page 308.
• The Conductivity monitor needs to be calibrated
Check calibration with a solution with known conductivity.
Calibrate the Conductivity monitor, see Section 7.7.3 Calibrate
the Conductivity monitor, on page 308.
Conductivity measurement
with the same buffer ap-
pears to decrease/increase
over time.
368 ÄKTA pure User Manual 29119969 AB
8 Troubleshooting
8.3 Troubleshooting: Monitors