Scan Type
Use
Parameter
Type
Parameter
Location
All
The CAD parameter controls the pressure of
CAD gas in the collision cell. The collision
gas helps to focus the ions as they pass
through the collision cell; the preset for the
CAD parameter is in fixed mode. For MS/MS
scan types, the CAD gas helps to fragment
the precursor ions. When the precursor ions
collide with the collision gas, they dissociate
to form product ions.
Use the preset value and optimize for the
compound.
Source and gas
CAD Gas
2
TOF MS, TOF MS/MS
The CE parameter controls the potential
difference between the Q0 region and the
Q2 collision cell. It is used only in MS/MS
scan types. This parameter is the amount of
energy that the precursor ions receive as
they are accelerated into the Q2 collision
cell, where they collide with gas molecules
and fragment.
Use the preset value and optimize for the
compound.
Compound
Collision
Energy (CE)
2
TOF MS/MS
The CES parameter, in conjunction with the
CE parameter, determines which three
discreet collision energies are applied to the
precursor mass in an Product Ion scan when
CES is used. The collision energy is ramped
from low to high. For example, in positive
mode, the collision energy will be ramped
from CE – CES to CE + CES. By entering a
CES value, collision energy spread is
automatically turned on.
Use the preset value and optimize for the
compound.
Compound
Collision
Energy
Spread (CES)
2
System User Guide
TripleTOF
®
5600/5600+ System
RUO-IDV-05-7040-B
58 / 131
Operating Instructions — Acquisition Methods
