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Run the
Verify Performance Only
option at any time. However, tune the instrument only if a loss of sensitivity
or resolution is noticed. For more information about tuning and calibration, refer to the
Advanced User Guide
.
For tuning the system, use the following solutions that come with the installation kit:
For positive mode:
• For optimizing TOF MS - Product Ion High Resolution or Product Ion High Sensitivity, use the Tuning Solution.
• For Q1 calibration, use the PPG POS solution.
In negative mode:
• For optimizing TOF MS - Product Ion High Resolution or Product Ion High Sensitivity, use Taurocholic acid.
Note:
We recommend that after using the Taurocholic acid, repeat the channel alignment using the PPG
POS solution.
• For Q1 calibration, use the PPG POS solution.
Tip!
Perform maintenance tasks regularly to make sure that the mass spectrometer is performing optimally.
Prerequisites
• The spray is stable and the correct tuning solution is being used.
• A printer is configured.
Required Materials
• Tuning solutions that are supplied in the Standards Chemical Kit shipped with the system. If required, a new
kit can be ordered from SCIEX. Refer to
.
• Gas-tight syringe (1.0 mL recommended)
• Red PEEK sample tubing.
Optimize the Mass Spectrometer
The following procedure describes how to verify the performance of the mass spectrometer. For more information
about using the other instrument performance options, refer to the Help.
TripleTOF
®
5600/5600+ System
System User Guide
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RUO-IDV-05-7040-B
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Tune and Calibrate