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TripleTOF

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System User Guide

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RUO-IDV-05-7040-B

Operational Precautions and Limitations

Содержание TripleTOF 5600

Страница 1: ...TripleTOF 5600 5600 System System User Guide January 2018 RUO IDV 05 7040 B...

Страница 2: ...does not imply any right and or license to use or permit others to use such manufacturers and or their product names as trademarks SCIEX warranties are limited to those express warranties provided at...

Страница 3: ...oratory Conditions 14 Operating Conditions 14 Performance Specifications 15 Equipment Use and Modification 15 Contact Us 16 Technical Support 16 Documentation Symbols and Conventions 16 Related Docume...

Страница 4: ...ent 51 Add a Period 51 Copy an Experiment into a Period 52 Copy an Experiment within a Period 52 Create an Acquisition Method using the Method Wizard 52 Scan Techniques 53 Single Mass Spectrometry 53...

Страница 5: ...Generate TWCs 87 Adjust the Threshold 87 Chromatogram Panes 88 Spectra Panes 89 Graphical Data Processing 89 Graphs 90 Manage Data 90 Zoom In on the Y axis 92 Zoom In on the X axis 92 10 Service and M...

Страница 6: ...Calibration Ions 110 B Exact Masses and Chemical Formulas 113 C Toolbar Icons 116 D Glossary of Symbols 125 E Glossary of Warnings 130 System User Guide TripleTOF 5600 5600 System RUO IDV 05 7040 B 6...

Страница 7: ...t in serious injury This safety information is intended to supplement federal state provincial and local environmental health and safety EHS regulations The information provided covers system related...

Страница 8: ...these standards EN 61010 1 EN 61010 2 061 Waste Electrical and Electronic Equipment WEEE Waste Electrical and Electronic Equipment 2012 96 EEC as implemented in EN 40519 Refer to Waste Electrical and...

Страница 9: ...management practices to control electrical cables This will reduce the chance of a tripping hazard For information about system electrical specifications refer to the Site Planning Guide AC Mains Sup...

Страница 10: ...grounding cable is connected between the sample loop and an appropriate grounding point at the ion source This supplementary grounding will reinforce the safety configuration specified by SCIEX Chemi...

Страница 11: ...storage handling and disposal of biohazardous toxic or radioactive materials Recommended Use secondary containment trays beneath the roughing pump the solvent bottles and the waste collection containe...

Страница 12: ...e Employee FSE Any toxic or injurious materials introduced into the equipment will be present in the source exhaust output Dispose of sharps following established laboratory safety procedures Environm...

Страница 13: ...t for the equipment can be maintained so that the device will perform as intended If the power supply line is subject to high electrical noise then install a surge protector Electromagnetic Interferen...

Страница 14: ...uipment WEEE To safely dispose of this equipment contact a local Customer Service office for complimentary equipment pick up and recycling Qualified Personnel Only qualified SCIEX personnel shall inst...

Страница 15: ...d Do not remove the covers Removing the covers might cause injury or malfunctioning of the system The covers need not be removed for routine maintenance inspection or adjustment Contact a SCIEX Field...

Страница 16: ...rity For the latest guidance on cybersecurity for SCIEX products visit sciex com Documents brochures win7 SecurityGuidance pdf Technical Support SCIEX and its representatives maintain a staff of fully...

Страница 17: ...d procedures in the text for a specific need and provides shortcuts but is not essential to the completion of a procedure Related Documentation To find software product documentation refer to the rele...

Страница 18: ...ished safe lifting procedures Refer to the Site Planning Guide for the weights of system components The TripleTOF 5600 system includes the following components A TripleTOF 5600 mass spectrometer with...

Страница 19: ...e DuoSpray TM ion source 2 Refer to Adjust the Integrated Syringe Pump Position on page 26 Syringe pump 3 Refer to Panel Symbols Mass spectrometer status LEDs 4 Contact an SCIEX Field Service Employee...

Страница 20: ...ction for the TDC card 8 Figure 2 2 Left Side View For more information Description Item Contact an FSE Gas and vacuum bulkhead 1 Contact an FSE Roughing pump vacuum connection 2 Refer to the CDS Oper...

Страница 21: ...Up the System on page 24 Mains supply connection 10 Contact an FSE Curtain Gas TM nitrogen supply connection 11 Contact an FSE Gas 1 and Gas 2 zero supply connection 12 Contact an FSE Source exhaust...

Страница 22: ...ision cell The Q1 quadrupole works in two operational modes Passing all ions within a specified m z range to the Q2 collision cell This is a TOF MS scan All ions are analyzed by the TOF system Passing...

Страница 23: ...ork with the system controller and the associated firmware to control the system and data acquisition During system operation the acquired data is sent to the Analyst TF software where it can be shown...

Страница 24: ...lanning Guide includes information on the mains supply and connections compressed air nitrogen roughing pump ventilation exhaust and site clearance requirements Contact us for a copy of the Site Plann...

Страница 25: ...a length of time then leave it in Standby mode with the ion source in place If the mass spectrometer must be shut down then follow these instructions Do not turn off the roughing pump until after the...

Страница 26: ...ains supply outlet Adjust the Integrated Syringe Pump Position WARNING Puncture Hazard Take care when handling the syringe The tip of the syringe is extremely sharp WARNING Puncture Hazard Make sure t...

Страница 27: ...the syringe is flush against the base and that the shaft of the syringe rests in the cutout 3 Adjust the post so that it triggers the automatic syringe stop before the syringe plunger hits the bottom...

Страница 28: ...st Adjust the height to prevent the syringe plunger from hitting the syringe during sample infusion 2 Post lock screw Tighten the screw after the height of the post is adjusted 3 4 Turn the side screw...

Страница 29: ...yringe pump click Stop Syringe Reset the Syringe Pump If the Analyst TF software stops communicating with the syringe pump then reset the syringe pump Use a paper clip or similar tool to press the res...

Страница 30: ...Figure 3 4 Reset Button System User Guide TripleTOF 5600 5600 System RUO IDV 05 7040 B 30 131 Operating Instructions Hardware...

Страница 31: ...sing projects and subprojects facilitates data management and makes comparison of results easier Create Projects and Subprojects on page 42 Create projects to store data 2 This is the process of optim...

Страница 32: ...perating Instructions Acquisition Methods on page 50 Create an acquisition method 2 After creating an acquisition method run samples by creating an acquisition batch and submitting the batch to the ac...

Страница 33: ...or PeakView software to analyze data For more information refer to the documentation that comes with the software MultiQuant TM software PeakView software Analyze data and print reports using companio...

Страница 34: ...must include a mass spectrometer Before creating an acquisition method make sure that all devices to be used in the method are included in the hardware profile including the syringe pump The devices c...

Страница 35: ...e Configuration Editor Dialog 2 In the Hardware Configuration Editor dialog click New Profile TripleTOF 5600 5600 System System User Guide 35 131 RUO IDV 05 7040 B Operating Instructions Hardware Prof...

Страница 36: ...ate New Hardware Profile Dialog 3 Type a name in the Profile Name field 4 Click Add Device System User Guide TripleTOF 5600 5600 System RUO IDV 05 7040 B 36 131 Operating Instructions Hardware Profile...

Страница 37: ...spectrometer and then click OK to return to the Create New Hardware Profile dialog 6 Click Setup Device 7 Optional To configure mass spectrometers that use the integrated syringe pump on the Configura...

Страница 38: ...ired 10 Click OK to return to the Create New Hardware Profile dialog 11 Click Add Device and then add and set up each device that is used with the mass spectrometer Refer to Add Devices to a Hardware...

Страница 39: ...nfigured to enable the software to communicate with them When the software is installed the driver required for each device is also installed After the devices are physically connected to the computer...

Страница 40: ...ng serial communication make sure that the serial port selected matches the serial port to which the device is physically connected Note The Alias field might also be referred to as the Name box and m...

Страница 41: ...e hardware profile does not have to be deactivated before another one is activated Click an inactive hardware profile and then click Activate Profile The other profile is deactivated automatically 16...

Страница 42: ...e experiment Use projects and subprojects for each experiment to better manage data and compare results For example use subprojects to store the results for specific dates Create Projects and Subproje...

Страница 43: ...en use the arrow buttons to move them to the Subproject folders list 4 If subprojects are used In the Subproject name field type a name for the first subproject or use the existing date 5 Optional To...

Страница 44: ...Subproject The Copy Subproject dialog is shown 2 Click Browse to navigate to the subproject source 3 Click OK 4 Select the subproject from the Source Subproject list 5 Click Browse to navigate to the...

Страница 45: ...e acquisition methods used during automatic tuning The API Instrument folder also contains data files for manual tuning runs that were performed using the Start button rather than the Acquire button T...

Страница 46: ...ore than one mass spectrometer when the folder is named For example API Instrument_instrument model3_010107 Recover the API Instrument Folder Back up the API Instrument folder regularly and after rout...

Страница 47: ...e channel alignment using the PPG POS solution For Q1 calibration use the PPG POS solution Tip Perform maintenance tasks regularly to make sure that the mass spectrometer is performing optimally Prere...

Страница 48: ...rate and then click CDS Inject Note Make sure that the correct Calibrant Valve Position is selected in the Reference Table Editor for the chosen reference table CDS can select from up to four differe...

Страница 49: ...ta Projects API Instrument Data Instrument Optimization yyyy mm dd results doc where yyyy mm dd is the date on which the report was created Users can print the Results Summary or open a previously sav...

Страница 50: ...ation about roles and security Create an Acquisition Method Using the Acquisition Method Editor Tip If users are creating a new acquisition method file from an existing file then some or all of the pe...

Страница 51: ...e on the period where the experiment is to be added right click and then click Add experiment Figure 7 1 Add Experiment An experiment is added below the last experiment in the period Note An experimen...

Страница 52: ...method can be saved in an existing project Tip To copy the Method Wizard template methods into the Acquisition Methods folder in the project folder select the Copy method templates check box in the Cr...

Страница 53: ...es the following mass spectrometry techniques to analyze samples Two modes of single mass spectrometry MS Quadrupole based single mass spectrometry for Q1 calibration only Time of flight based single...

Страница 54: ...ometry In a product ion scan Product Ion the system generates mass spectrometric information by selecting a particular precursor ion window in Q1 fragmenting in Q2 a collision cell and pulsing the ion...

Страница 55: ...ameters are the set of instrument parameters currently being used Source and gas parameters These parameters can change depending on the ion source used Compound parameters These parameters consist mo...

Страница 56: ...e heater and is only available if the NanoSpray ion source and interface are installed The optimal heater temperature depends on the type of sample being analyzed and the solvent used If the heater te...

Страница 57: ...ter controls the gas flow of the Curtain Gas TM interface The Curtain Gas TM interface is located between the curtain plate and the orifice It prevents the contamination of the ion optics Source and g...

Страница 58: ...parameter is the amount of energy that the precursor ions receive as they are accelerated into the Q2 collision cell where they collide with gas molecules and fragment Use the preset value and optimiz...

Страница 59: ...e Delay IRD 3 MS MS only Enhanced This is the width or duration of the ion pulse in milliseconds and is calculated based on the IRD The range is typically 5 to 328 msec with a default value of 10 msec...

Страница 60: ...hod After all of the samples have been acquired the queue stops and the mass spectrometer goes into Standby mode In Standby mode the LC pumps and some instrument voltages are turned off The user can c...

Страница 61: ...heck box to keep the mass spectrometer running after analysis has been completed This feature allows the heaters and gases to continue running even after devices have entered Idle state so that the io...

Страница 62: ...Samples to a Batch A set can consist of a single sample or multiple samples Note For more information about adding quantitation information to a batch refer to the Advanced User Guide 1 On the Navigat...

Страница 63: ...a name for the data file that will store the sample information 9 Select the Set name check box to use the set name as part of the data file name 10 Select the Auto Increment check box to increment th...

Страница 64: ...isted in the method in the Inj Volume L column type the injection volume for each sample 16 To set sample locations do one of the following Set Sample Locations in the Batch Editor on page 67 Select V...

Страница 65: ...les field type the number of samples to be acquired between calibration samples 3 From the Calibrant Reference Table select a table from the list of all calibrant reference tables available for the cu...

Страница 66: ...s started Also if the system has been previously run that day and has not yet been set to Standby mode then sample acquisition will start automatically 1 Make sure that the column oven temperature is...

Страница 67: ...e or tray 3 Save the file Select Vial Positions Using the Locations Tab Optional 1 Click the Locations tab in the Batch Editor 2 Select the set from the Set list 3 Select the autosampler from the Auto...

Страница 68: ...y while clicking the first and last vial within a set To perform multiple injections from the same vial press the Ctrl key while clicking the vial location The red circle changes to a green circle Sto...

Страница 69: ...ferent name Save As Batch Saves the batch as a template Save As a Template Hides or shows a column Hide Show Column Saves the batch column settings Save Column Settings Adds a custom column Add Custom...

Страница 70: ...ueue Queue States The current state of the queue is indicated in the Queue Server Figure 8 7 Queue Server Indicator Showing Normal Mode Figure 8 8 Queue Server Indicator Showing Tune Mode The first ic...

Страница 71: ...and are ready to run In this state the queue can receive samples and will run after samples are submitted Ready The system will automatically begin acquisition when the next sample is submitted Waitin...

Страница 72: ...uld be equilibrated before it is ready to run If the background color is green the device is ready to run Green or yellow Idle The device is equilibrating Green or yellow Equilibrating The device is w...

Страница 73: ...serts a pause in seconds between two samples Insert Pause Deletes either the batch or the selected samples Delete Moves the batch within the queue Move Batch Sorts on the preselected column Sort Chang...

Страница 74: ...rum right click the mass spectrum and then click Show Last Scan If there is a check mark beside Show Last Scan then the spectrum will update in real time 1 On the Navigation bar under Explore double c...

Страница 75: ...s and cycles including instrument parameters and the HPLC device method LC pump flow rate In addition it also contains the MS resolution and mass calibration tables used for the sample acquisition Tab...

Страница 76: ...pecify Compound Information dialog Select the IDs and molecular weights to be saved in the compound database Save Acquisition Method to CompoundDB Deletes the selected pane Delete Pane Show Data in Ta...

Страница 77: ...ab Function Menu Opens the Select Columns for Peak List dialog Column Options Saves the data as a txt file Save As Text Deletes the selected pane Delete Pane TripleTOF 5600 5600 System System User Gui...

Страница 78: ...lable acquire the data and the mass spectrometer data simultaneously and then save it in the same file 1 Make sure that the Example folder is selected 2 On the Navigation bar under Explore double clic...

Страница 79: ...ers whichever is active 5 Optional To remove the colored peaks right click in the Peak List tab and then clear Show Peaks in Graph Chromatograms A chromatogram is a graphical view of the data obtained...

Страница 80: ...g intensity values at a single discrete mass value or a mass range from a series of mass spectral scans It indicates the behavior of a given mass or mass range as a function of time XIC Extracted Ion...

Страница 81: ...taining a TIC select a range 2 Click Explore Show Show Spectrum The spectrum opens in a new pane Tip Double click in the TIC pane at a particular time to show the spectrum Figure 9 4 Example of a TIC...

Страница 82: ...he selected area This option creates an XIC using the maximum mass from the selected spectral range Yes No Maximum Can be used only with Base Peak Chromatograms BPCs Use the Use Base Peak Masses comma...

Страница 83: ...e contains the mass range and the maximum intensity in counts per second Generate an XIC Using Base Peak Masses 1 Open a data file containing spectra 2 In a BPC select the peak from which to extract i...

Страница 84: ...ass range 4 Click OK An XIC of the selection opens below the chromatogram pane The experiment information at the top of the pane includes the masses and the maximum intensity in counts per second Gene...

Страница 85: ...Intensity field 6 Type the mass that determines the beginning of the scan range in the Minimum Mass field 7 Type the mass that determines the end of the scan range in the Maximum Mass field 8 To set...

Страница 86: ...below the DAD spectrum DAD Data Like mass spectrometer data DAD data can be viewed in chromatogram or spectrum form Users can view the DAD spectrum for a single point in time or for a range of time as...

Страница 87: ...trum and then click Show DAD TWC Adjust the Threshold The threshold is an invisible line drawn parallel to the X axis of a graph that sets a limit below which the software will not include peaks in a...

Страница 88: ...tic Wizard Spectral Arithmetic Wizard Generates a text file containing the data in a pane which can be opened in Microsoft Excel or other programs Save to Text File Saves information about changes to...

Страница 89: ...n at the cursor position in the pane Add Caption Adds a text box at the cursor position in the pane Add User Text Shows the scan prior to the selection Show Last Scan In this dialog select the paramet...

Страница 90: ...re performing processing operations such as smoothing or subtraction A window contains one or more panes arranged in such a way that all the panes are fully visible and they do not overlap Panes can b...

Страница 91: ...arget pane then the pane moves to the left or right of that pane respectively If the pane is at any other position then the pane moves to the target row The drop shadow of the pane as the pane is move...

Страница 92: ...Take care when zooming in on the baseline Zoom in too far and the zoom in box closes 2 Release the mouse button to draw the graph to the new scale Zoom In on the X axis Tip To return the graph to the...

Страница 93: ...emicals have been used with the system Recommended Maintenance Schedule Table 10 1 provides a recommended schedule for cleaning and maintaining the system Tip Perform maintenance tasks regularly to ma...

Страница 94: ...needed Orifice plate front and rear Contact the local QMP or FSE Clean As needed QJet ion guide and IQ0 lens Contact the local QMP or FSE Clean As needed Q0 rod set and IQ1 lens Contact the local QMP...

Страница 95: ...n the Surfaces Clean the external surfaces of the mass spectrometer after a spill or when they become dirty CAUTION Potential System Damage Use only the recommended cleaning methods and materials to a...

Страница 96: ...sues are observed then clean the mass spectrometer front end Required Materials Note U S customers can call 877 740 2129 for ordering information and inquiries International customers can visit sciex...

Страница 97: ...fety Data Sheets and follow all of the recommended safety procedures when handling storing and disposing of chemicals For health and safety precautions refer to the System User Guide WARNING Ionizing...

Страница 98: ...terface such as the curtain plate might require several cleanings using multiple wipes Only dampen the wipe or swab slightly when applying water or cleaning solution Water more often than organic solv...

Страница 99: ...e Curtain Plate CAUTION Potential System Damage Do not rest the curtain plate or orifice plate on the aperture tip Make sure that the conical side of the curtain plate faces up CAUTION Potential Syste...

Страница 100: ...e water and then clean both sides of the curtain plate Note Use multiple wipes as required 3 Repeat step 2 using the cleaning solution 4 Using a dampened wipe or small poly swab clean the aperture 5 W...

Страница 101: ...the orifice plate is dry 4 Inspect the orifice plate for solvent stains or lint removing any residue with a clean slightly damp lint free wipe Note Persistent spotting or filming is an indicator of co...

Страница 102: ...aust drain bottle regularly and empty it before it becomes full Also inspect the bottle and its fitting for leaks and tighten connections or replace components if required Follow the steps in this pro...

Страница 103: ...s spectrometer and the lab vent are secured with hose clamps 3 Disconnect the hoses from the cap 4 If applicable lift the drain bottle out of the holder 5 Remove the cap from the drain bottle 6 Empty...

Страница 104: ...ometer Prerequisite Procedures Shut down the system by following the procedure in the System User Guide WARNING Environmental Hazard Do not dispose of system components in municipal waste Follow local...

Страница 105: ...n Filters 2 Remove the filter and then replace it with a new one Figure 10 7 Cooling Fans Filter Description Item Cooling fans cover 1 Filter 2 3 Install the filter cover TripleTOF 5600 5600 System Sy...

Страница 106: ...act a SCIEX FSE for decommissioning information To disconnect power from the mass spectrometer remove the mains supply connector from the AC mains supply Note The ion source and mass spectrometer must...

Страница 107: ...as occurred because the vacuum pressure is too high Contact the local QMP or FSE 1 Ambient temperature is too high A system fault has occurred because the QPS exciter module temperature is too high 1...

Страница 108: ...rifice plate is dirty 5 The QJet ion guide or IQ0 lens is dirty 6 The Q0 region is dirty 7 The syringe or sample line is leaking 8 The sample has degraded or has a low concentration 9 The probe is not...

Страница 109: ...ts 1 The probe is not optimized 2 The sample was not prepared correctly or the sample has degraded 3 The sample inlet fittings are leaking The mass spectrometer performance has degraded Turn the coron...

Страница 110: ...409 933 63665 585 38549 411 25991 44 99819 Table A 3 APCI Positive Calibration Solution and ESI Positive Calibration Solution TOF MS Masses TOF MS 146 11756 aminoheptanoic acid 266 15981 amino dPEG 4...

Страница 111: ...Solution TOF MS Masses TOF MS 144 103 7 aminoheptanoic acid 264 14526 amino dPEG 4 acid 277 09825 sulfinpyrazone fragment 352 19769 amino dPEG 6 acid 403 11219 sulfinpyrazone 440 25012 amino dPEG 8 a...

Страница 112: ...able A 7 APCI Negative Calibration Solution and ESI Negative Calibration Solution MSMS Sulfinpyrazone Fragment Masses MSMS Sulfinpyrazone Fragment 77 03967 C6H5 116 0506 C8H6N 130 0662 C9H8N 158 0611...

Страница 113: ...2810 134 09428 2 237 13433 114 10189 175 13286 210 16996 192 13614 3 295 17619 143 12282 233 17472 268 21182 250 17800 4 353 21805 172 14375 291 21658 326 25368 308 21986 5 411 25991 201 16468 349 258...

Страница 114: ...21 1339 92967 665 49956 1277 92820 1312 96530 1294 93148 22 Reserpine Table B 2 Reserpine Exact Masses Reserpine C33H40N2O9 Mass Description 609 28066 Molecular Ion C33H41N2O9 448 19659 Fragment C23H...

Страница 115: ...NO3S 79 95736 Fragment SO3 TOF Calibration Solution Table B 4 TOF Calibration Solution Exact Masses Mass Description 132 90488 Molecular Ion Cs 829 53933 Molecular Ion Peptide ALILTLVS TripleTOF 5600...

Страница 116: ...py Subproject Table C 2 Acquisition Method Editor Icons Description Name Icon Click to show the MS tab in the Acquisition Method editor Mass Spec Right click to add an experiment add an IDA Criteria L...

Страница 117: ...ue Inserts a pause in the queue Pause Sample Now Inserts a pause before a specific sample Insert Pause before Selected Sample s Continues acquiring the sample Continue Sample Starts a new period Next...

Страница 118: ...the mass spectrometer Calibrate from spectrum Opens the Manual Tune Editor Manual Tune Verifies the instrument performance adjusts the mass calibration or adjusts mass spectrometer settings Instrument...

Страница 119: ...ns the Baseline Subtract dialog Baseline Subtract Adjusts the threshold Threshold Shows the Noise Filter Options dialog which can be used define the minimum width of a peak Signals below this minimum...

Страница 120: ...tions performed on a particular file such as smoothing subtraction calibration and noise filtering Show History Opens the compound database Open Compound Database Adjusts the threshold Set Threshold S...

Страница 121: ...nction Name Icon Click to open files Open File Click to navigate to the next sample Show Next Sample Click to navigate to the previous sample Show Previous Sample Click to open the Select Sample dialo...

Страница 122: ...that you want to view in greater detail Expand Selection By Click to return the expanded selection to normal view Clear ranges Click to type start and stop points for a selection This provides more a...

Страница 123: ...e analyte chromatogram only Show Active Graph Shows the analyte and its associated chromatogram available only when an associated internal standard exists Show Both Analyte and IS Returns to the prese...

Страница 124: ...ens peaks in a pane Peak Review Pane Opens peaks in a window Peak Review Window Opens the calibration curve in a pane Calibration Pane Opens the calibration curve in a window Calibration Window Shows...

Страница 125: ...ity ACMA EMC Requirements Alternating current Amperes current A Authorized representative in the European community Biohazard CE Marking of Conformity cCSAus mark Indicates electrical safety certifica...

Страница 126: ...on the label or product indicates the date of manufacture China RoHS logo The device does not contain toxic and hazardous substances or elements above the maximum concentration values and it is an en...

Страница 127: ...prevent electric shock Hot Surface Hazard In Vitro Diagnostic Device Ionizing Radiation Hazard Keep dry Do not expose to rain Relative humidity must not exceed 99 Keep upright Laser Radiation Hazard L...

Страница 128: ...mber Toxic Chemical Hazard Transport and store the system within 66 kPa to 103 kPa Transport and store the system within 75 kPa to 101 kPa Transport and store the system within 10 to 90 relative humid...

Страница 129: ...3 0 connection Ultraviolet Radiation Hazard Volt Ampere power VA Volts voltage V WEEE Do not dispose of equipment as unsorted municipal waste Environmental Hazard Watts W yyyy mm dd Date of manufactur...

Страница 130: ...CATOR OR TILT INDICATOR ON THE WAYBILL BEFORE ACCEPTING SHIPMENT AND NOTIFY YOUR LOCAL AB SCIEX CUSTOMER SUPPORT ENGINEER IMMEDIATELY DO NOT UNCRATE CONTACT YOUR LOCAL CUSTOMER SUPPORT ENGINEER FOR UN...

Страница 131: ...T FIRST ENSURING BOTTLE CAP IS SECURED Note This warning is attached to the source exhaust waste bottle WARNING DO NOT OPERATE WITHOUT FIRST ENSURING BOTTLE CAP IS SECURED WARNING NO USER SERVICEABLE...

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