PROPRIETARY INFORMATION
CONFIDENTIAL MATERIAL
Assays/Reagents
Not for Customer Distribution
106
AEROSET
®
System Troubleshooting Guide
94816-107—November 2004
Amylase
Interference Information
Icodextrin, a complex carbohydrate contained in some fluids
used for peritoneal dialysis, has been reported to interfere with
amylase assays. Low amylase values may be obtained due to
inhibition of amylase activity by icodextrin. No testing has yet
been conducted for the specific amylase method used on the
AEROSET System. In addition, the mechanism of the reported
amylase inhibition may not affect all amylase assays. Until
specific information is available for the AEROSET, amylase
results from patients receiving peritoneal dialysis must be
assessed in relation to their clinical condition and exposure to
icodextrin.
Wang G, Leesch V, Turner P, Moberly JB, Martis L. Kinetic
analysis of icodextrin interference with serum amylase assays,
Adv Perit Dial
2002;18:96–99.
Anderstam B, Garcia-Lopez E, Heimburger O, Lindholm B.
Determination of alpha-amylase activity in serum and
dialysate from patients using icodextrin-based peritoneal
dialysis fluid,
Perit Dial Int
2003;23:146–50.
Содержание AEROSET
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