Teledyne CombiFlash EZ Prep, User Manual

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Section 8 Maintenance
8-17
plug is within the probe capillary. The occurrence of plugs can
be reduced by using a 0.45 µ syringe filter when injecting
samples for Method Development and Ionization Settings. To
troubleshoot an over pressure error, complete the following:
• If the error occurs during a run, select CONTINUE
WITHOUT PurIon, and the purification can continue
without the PurIon signal or peak detection, but will rely
on any other detector selected such as UV or ELSD. This
allows the run to be completed before troubleshooting
the plug.
• Use the menu item MS-> Manual control [MS M
ANUAL
C
ONTROL [6.3.9]
].
• Press the Start Carrier Pump button.
• Watch the pressure on the ribbon gauge.
• Loosen the fitting at the source inlet. If the pressure
drops, then the source capillary is plugged.
• If there is still an error or the pressure remains high,
then the plug is between that point and the splitter
valve (or the valve itself). Continue to loosen fittings
going back the to the splitter valve until the error is
corrected.
8.6.11 Check Valve Cleaning
If the check valves are allowed to dry out after using volatile
salts (e.g., ammonium acetate or ammonium formate), they
may stick and fail to function. Complete the following to clean
the check valves:
1. Remove the inlet and outlet lines from the check valve
holders (Figure 8-11), and then remove the check valve
holders. Pliers may be needed to remove the holders.