Biotek Synergy HTX, Operator'S Manual

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Chapter 4: Preventive Maintenance
Recommended Maintenance Schedule
Overview
A general
Preventive Maintenance (PM)
regimen for all Synergy HTX models
includes periodically cleaning all exposed surfaces and inspecting/cleaning the
Excitation and Emission filters. For models with the external dispense module,
additional tasks include flushing/purging the fluid path and cleaning the tip prime
trough, priming plate, supply bottles, internal dispense tubing, and injector heads.
Daily Cleaning for the Dispense Module
To keep the dispense module and injectors in top condition, flush and purge the fluid
lines with deionized (DI) water every day or upon completion of an assay run,
whichever is more frequent. Some reagents may crystallize or harden after use,
clogging the fluid passageways. Flushing the tubing at the end of each day, letting the
DI water soak them overnight, and then purging the lines at the beginning of each day
ensures optimal performance of the dispense system. Perform a visual inspection of the
dispensing accuracy before conducting an assay that requires a dispense step to verify
instrument performance.
It is important to keep the dispensing lines scrupulously clean at all times. Take special
care when using molecules active at very low concentrations (e.g., enzymes,
inhibitors). Remove any residual reagent in the dispensing lines using a suitable
cleaning solution (review the reagent’s package insert for specific recommendations).
A daily cleaning regimen is the best way to ensure accurate performance and a long
life for your instrument and dispense module. BioTek also recommends flushing the
module with DI water before conducting the decontamination procedure described in
Chapter 5, As-Needed Maintenance
.
BioTek Instruments, Inc.