Micromass Quattro Ultima, Руководство пользователя

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The Constant Neutral Loss Spectrum
The loss of a specific neutral fragment or functional group from an unspecified parent
or parents.
Typical applications:
•
Screening mixtures, for example during neonatal screening, for a specific class
of compound that is characterised by a common fragmentation pathway.
The scans of MS1 and MS2 are synchronised. When MS1 transmits a specific
parent ion, MS2 “looks” to see if that parent loses a fragment of a certain mass.
If it does it registers at the detector.
The result:
The “spectrum” shows the masses of all parents that actually lost a fragment of a
certain mass.
Data System
The PC based data system, incorporating MassLynx NT™ software, controls the mass
spectrometer detector and, if applicable, the HPLC system, autosampler, syringe
pump, divert valve or injector valve.
The PC uses the Microsoft Windows NT graphical environment with colour graphics
and provides for full user interaction with either the keyboard or mouse.
MassLynx NT provides full control of the system including setting up and running
selected HPLC systems, tuning, acquiring data and data processing.
Analog inputs can be read by the data system so that, where applicable, a trace from a
conventional LC detector (for example UV or fluorescence) can be stored
simultaneously with the acquired mass spectral data. A further option is the ability to
acquire UV photodiode array detector data.
Comprehensive information detailing the operation of MassLynx NT is contained in
the
MassLynx NT User’s Guide .
Instrument Description
Page 22
Quattro Ultima
User's Guide
MS1
scanning
MS2
scanning
Collision Cell
RF only
(pass all masses)