Waters Xevo TQ MS, Operator And Maintenance Manual, Page: 12 / 184

xii Table of Contents
Ion optics ............................................................................................................. 1-9
MS operating modes ....................................................................................... 1-10
MS/MS operating modes ................................................................................ 1-11
Product (daughter) ion mode......................................................................... 1-12
Precursor (parent) ion mode.......................................................................... 1-13
Multiple reaction monitoring mode .............................................................. 1-13
Constant neutral loss mode........................................................................... 1-14
ScanWave daughter scan mode..................................................................... 1-14
Leak sensors ..................................................................................................... 1-15
Vacuum system ................................................................................................ 1-15
Rear panel ......................................................................................................... 1-16
2 Preparing the Mass Spectrometer for Operation ........................... 2-1
Starting the mass spectrometer .................................................................... 2-2
Verifying the instrument’s state of readiness ................................................ 2-4
Monitoring the mass spectrometer LEDs....................................................... 2-4
Tuning and calibration information ............................................................... 2-4
Running the mass spectrometer at high flow rates ....................................... 2-5
Preparing the IntelliStart Fluidics system ................................................. 2-5
Installing the reservoir bottles........................................................................ 2-5
Purging the infusion pump.............................................................................. 2-7
Rebooting the mass spectrometer ................................................................. 2-8
Leaving the mass spectrometer ready for operation ............................... 2-9
Emergency shutdown of the mass spectrometer ....................................... 2-9
3 Preparing the ESI Source .................................................................... 3-1
ESI mode ............................................................................................................. 3-2
Installing the ESI probe .................................................................................. 3-2
Removing the ESI probe.................................................................................. 3-6