Waters Xevo TQ MS, Operator And Maintenance Manual, Page: 28 / 184

1-12 Waters Xevo TQ MS Overview
Product (daughter) ion mode
Product ion mode is the most commonly used MS/MS operating mode. You can
specify an ion of interest for fragmentation in the collision cell, thus yielding
structural information.
Product ion mode
Typical applications
You typically use product ion mode for the following applications:
• Method development for MRM screening studies:
–
Identifying product ions for use in MRM transitions.
– Optimizing CID tuning conditions to maximize the yield of a specific
product ion to be used in MRM analysis.
• Structural elucidation (for example, peptide sequencing).
MS1
Static (at precursor mass)
MS2
Scanning
Collision cell
Pass all masses