Waters Xevo TQ MS, Operator And Maintenance Manual, Page: 73 / 184

Cleaning the source components 4-25
Cleaning the source components
Clean the sample cone and cone gas nozzle when these conditions apply:
• The sample cone and cone gas nozzle are visibly fouled.
• LC and sample-related causes for decreased signal intensity have been
dismissed.
See “Cleaning the sampling cone assembly” on page 4-26 .
If cleaning the sample cone and cone gas nozzles fails to increase signal
sensitivity, also clean the extraction cone. See “Cleaning the extraction cone”
on page 4-35 .
If cleaning the extraction cone fails to increase signal sensitivity, clean the ion
block and isolation valve. See “Cleaning the ion block assembly” on page 4-42 .
If cleaning the ion block and isolation valve fails to increase signal sensitivity,
also clean the source hexapole assembly. See “Cleaning the source hexapole
assembly” on page 4-53 .