Thermo Scientific VF-F20-A, Operating Manual

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2
•
Safety
Page 28 Integral Fraction Collector FT (VF-F20-A) Operating Manual
2.4 Solvent and Additive Information
2.4.1 General Compatibility
To protect optimal functionality of the Vanquish system, observe these
recommendations on the use of solvents and additives:
•
The system must be used with reversed-phase (RP) compatible
solvents and additives only.
•
Use only solvents and additives that are compatible with all parts in
the flow path.
2.4.2 Allowed pH Ranges
Allowed pH ranges (standard system configuration):
System
(Standard
Configuration) Allowed
pH ranges Remarks
Vanquish Core Limited to
2-12 by
Integral
Fraction
Collector
•
pH values of 2 or less : The application time should
be as short as possible. Flush the system
thoroughly after these applications.
•
pH values higher than 9.5 with optical detectors :
Avoid using mobile phases with a pH value higher
than 9.5 together with optical detectors. This can
impair the functionality and optical performance of
the detector flow cell.
•
pH values higher than 12 : May affect
electrochemical detection. Before using highly
alkaline solvents for flushing the system,
disconnect the detector from the system.
•
Mobile phases containing ammonium hydroxide : In
rare cases, a shortened lifetime of reversed-phase
(UHMW-PE) piston seals has been observed with
high pH, ammonium hydroxide containing mobile
phases and prolonged exposure.
Vanquish
Horizon
Vanquish Flex
2-12