4
Purpose, Overview and Features of the Product
The rate constants of each PK/PD model are as follows:
Tốc độ
không đổi
Propofol
(Marsh)
Propofol (Schnider)
Remifentanil (Minto)
Vc (V1) [L]
0.228 x Weight
4.27
5.1-0.0201 x (Age-40)+0.072 x (LBM-55)
k
10
[/min]
0.119
[1.89+((Weight-77) x 0.0456)+((59 x 0.0681)-
(LBM x 0.0681))+((Height-177) x 0.0264)]/Vc
[2.6-0.0162 x (Age-40)+0.0191 x (LBM-55)]/
Vc
k
12
[/min]
0.112
[1.29-0.024 x (Age-53)]/Vc
[2.05-0.0301 x (Age-40)]/Vc
k
13
[/min]
0.0419
0.836/Vc
[0.076-0.00113 x (Age-40)]/Vc
k
21
[/min]
0.055
[1.29-0.024 x (Age-53)]/[18.9-0.391 x (Age-53)] [2.05-0.0301 x (Age-40)]/[9.82-0.0811 x
(Age-40)+0.108 x (LBM-55)]
k
31
[/min]
0.0033
0.0035
[0.076-0.00113 x (Age-40)]/5.42
k
e0
[/min]
0.26
0.456
0.595-0.007 x (Age-40)
Tài liệu tham
khảo
Marsh et al.:
British Journal
of Anaesthesia
1991; 67: 41-48
Schnider et al.: Anesthesiology 1999; 90:
1502 - 1516
Anesthesiology 1998; 88:
1170 - 1182
Minto et al.: Anesthesiology 1997; 86:
10 - 23
Features
TCI mode
• TCI (Target Controlled Infusion) can be performed with this product in the following five different combinations of drugs, models,
and targets:
For Plasma TCI, Propofol (Marsh), Propofol (Schnider), and Remifentanil (Minto) are available.
For Effect-site TCI, Propofol (Schnider) and Remifentanil (Minto) are available.
Dose unit
• The flow rate (mL/h) can be automatically calculated based on the dose units such as
μ
g/kg/min. The calculated contents of the
flow rate can be checked on the screen.
Easy-to-read display
• With a 4.3 inch (10.9 cm) colour LCD, clear and precise visibility has been achieved.
• The operation indicator allows the operation/stop/alarm status to be easily recognised.
• The internal battery charge and level indicator is displayed on the LCD with 5 bars.
Wide range of alarm functions
• The alarm functions include Occlusion alarm, Pressure alarm, Nearly Empty alarm, Slider Displacement alarm, Syringe Barrel
Detection alarm, Syringe Displacement alarm, Link Interruption alarm, Plunger Displacement alarm, Battery alarm, Shutdown
Notice alarm, Power Failure alarm, Re-alarm, Start Reminder, No Flow Rate alarm, No VTBI alarm*
1
, Flow Rate/VTBI (Volume to
be infused) Volume Judgment alarm*
1
and Completion alarm*
1
.
*
1
: Only if the VTBI setting function is enabled (Default: disabled)
• The Occlusion alarm detection sensitivity level can be changed according to the condition of use.
• The Flow Rate/VTBI Volume Judgment alarm works as a safety function to prevent the normal mode operation if the flow rate is
equal to or more than the VTBI. (Default: disabled)
Additional safety functions
• The keypad lock function disables any switch operations after being set to prevent any operational errors or inadvertent
operations. (Except for Start switch, Power switch and Back/Mute switch (for operation to release the keypad lock).)
User-friendly shape and structure
• With a unit weight of approx. 2.0 kg, the carrying burden is reduced, and allows for stable installation with the pole clamp
included.
• The rounded-cornered body is easy to clean even when drug solution has adhered.
Dual power supply system
• Dual power supply system with AC power and internal battery
• The internal battery can provide approx. 8 hours of continuous operation for solution delivery at a flow rate of 5 mL/h at
temperature of 25°C, with a fully-charged new battery.
• The internal battery can be charged to approx. 80% in 3 hours.
• The sub-battery is used for a Power Failure alarm in case both power supplies are lost.
