Gambro Cobe Spectra, Essentials Manual

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Introduction
COBE
®
Spectra™ Apheresis System • Essentials Guide 2-5
Pumps
The Spectra system has four peristaltic-type pumps with removable
rotors for easy cleaning. The system automatically loads the pumps as it
pulls the pump cartridges onto the pumps. It reverses the action for
automatic unloading.
Anticoagulant (AC) pump : Pumps anticoagulant from the AC container
to the inlet line. During a WBC granulocyte (PMN) removal procedure,
it pumps a prescribed starch/sodium citrate solution to the inlet line.
Inlet pump : Pumps anticoagulated whole blood from the donor/patient
access to the centrifuge.
Plasma/RBC pump : Pumps plasma from the centrifuge to a collection
bag, or to recombine with cellular components for return to the donor or
patient during an ELP, AutoPBSC, LRS, LRST, TPE, or WBC
procedure. Pumps RBCs from the centrifuge to the RBC waste bag
during an RBCX procedure.
Collect/replace pump : Pumps cells from the centrifuge to the collection
bag, or pumps replacement fluid or RBCs from the replacement fluid
container for return to the patient.
Cartridge clamp : Retracts to facilitate pump loading. After the pumps
are loaded, the clamps hold the pump cartridges in place.
Valves
The Spectra system has five valves. Four are pinch-type valves with a post
that rotates off and on tubing to open and close it. The fifth valve—the
return line valve—is a solenoid fail-safe clamp, which clamps the return
line during power loss or certain alarm conditions.
All five valves have an open or load position to enable loading or
unloading of the disposable tubing set.
Waste divert valve : Two-way valve (upper) and three-way valve (lower)
that operate in conjunction. The valve assembly opens to direct saline to
the waste bag during Prime mode. It also opens to remove air from the
inlet and return air chambers, and functions during the recirculation
step of Rinseback mode.
Plasma/RBC valve : Three-way valve that directs plasma to a plasma bag;
or for recombination with cellular components for return to the donor
or patient during ELP, AutoPBSC, LRS, LRST, TPE, and WBC
procedures. During ELP, LRS, LRST, and WBC procedures, the valve
moves only in Manual mode. Re-entering Automatic mode during a
WBC procedure causes the valve to move back to the return position,
allowing return of the plasma to the donor/patient. During RBCX
procedures, the valve directs RBCs to the RBC waste bag.
Collect/replace valve : Three-way valve that directs flow to the collection
bag or returns it to the donor during an RBC spillover (to protect the
platelet product). During a plasma exchange procedure, it allows
replacement fluid to be pumped from the container to the patient.
During an RBCX procedure, it allows replacement RBCs to be pumped
from the container for recombination with plasma for return to the
patient. During an AutoPBSC procedure, it allows return of platelets to
the donor/patient, and during the Harvest and Chase phases, it diverts
MNCs and plasma to the collection bag.
RBC/plasma line valve : Two-way valve in the same housing as the RBC
detector that closes during Prime mode to allow air to exit the channel
before the channel is primed, and closes during the Rinseback mode to
collapse the channel.
Return line valve : Two-way valve that closes during a power loss and
some alarm conditions (certain system, air, and pressure alarms and any
alarm that stops the centrifuge). During Single-Needle procedures, it
opens and closes during the Draw and Return phases of each Single-
Needle cycle.