Gambro Cobe Spectra, Essentials Manual

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Preface
1-14 COBE
®
Spectra™ Apheresis System • Essentials Guide
Caution: Once fluid has entered the disposable tubing set, DO
NOT disturb sensors in pressure sensor housings. Disturbance
prevents transducers from accurately monitoring pressures.
Caution: During BMP procedures, whenever the RBC volume is
greater than 215 mL, the BMP procedure automatically collects
plasma during the first volume of bone marrow processed.
Therefore, you MUST connect a plasma bag to the plasma line luer
connection of the WBC set.
Caution: ACD-A is the approved anticoagulant for ELP, LRS, and
LRST collection procedures and the preferred anticoagulant for
AutoPBSC, RBCX, TPE, and WBC removal procedures using the
Spectra system. If you use heparin for a TPE procedure, see
“Using Heparin Instead of ACD-A” in Chapter 2 of the Therapeutic
Apheresis Guide. For granulocyte (PMN) removal, use hydroxyethyl
starch/sodium citrate concentrate. The attending physician is
responsible for administration of the type, amount, and rate of
anticoagulant. All personnel involved in apheresis procedures
should familiarize themselves with the anticoagulant
manufacturer’s product insert.
Caution: To avoid damage to the tubing set, DO NOT stretch the
tubing when folding the channel for installation in the centrifuge.
DO NOT pull on the tubing connected to the LRS chamber. This
can damage the LRS chamber.
Caution: You MUST use the dual-stage filler with LRS bracket for
LRS procedures, and the black LRS Turbo filler for LRS Turbo
procedures.
Caution: The disposable tubing set is sterilized with ethylene
oxide. The blood and fluid pathways of the disposable tubing sets
are sterile and nonpyrogenic. To avoid contamination of blood and
fluids, DO NOT use a disposable tubing set if the end caps are not
in place.
Caution: Patients or donors with impaired or abnormal citrate
and/or calcium metabolism (e.g., liver and renal diseases) can
present an increased risk of citrate sensitivity. The attending
physician should assess the appropriateness of such patients or
donors for apheresis and prescribe how they should be monitored
during the apheresis procedure.
Caution: Ensure lines are attached to correct fluids:
•
AC line (orange spike) to the ACD-A container.
•
The spike on the access saline line and the needle on the
return saline line to the 0.9% NaCl container.
Caution: Ensure lines are attached to correct fluids:
•
AC line (orange spike) to the HES/sodium citrate container.
•
The spike on the access saline line and the needle on the
return saline line to the 0.9% NaCl container.
Caution: Ensure lines are attached to correct fluids:
•
AC line (orange spike) to the ACD-A or HES/sodium citrate
container.
•
The spike on the access saline line and the needle on the
return saline line to the 0.9% NaCl container.