Spectra Optia Apheresis System Operator’s Manual
171
Granulocyte (PMN) Collection Procedures
12
Monitoring the Run
The system displays information on the screens to help you monitor the progress of the run. To access the screens,
touch the
Run
menu button and then the tab for the screen you want to view. Be sure to verify that the volumes
displayed on the screens are consistent with the actual volumes in the fluid containers and in the bags.
See “Glossary of Terms” on page 278 for descriptions of the buttons on the screens.
Main Run Screen
The main run screen is the default run screen and displays or provides access to the information you most likely
need to monitor the run. If you want to return to the main run screen after viewing a different screen, touch the go
back button, the active menu button, or the tab for the current screen. There is no tab for the main run screen.
Collection Status Screen
To access the collection status screen, touch the
Collection Status
tab. Use this screen to monitor the progress of
the run and to adjust the collection preference. You can also use this screen to change the position of the collect
valve to immediately direct the flow of cells in the collect line into the reservoir for return to the patient, if
necessary.
Collection preference
The collection preference is a reference number that the system uses to adjust the plasma pump flow rate, which
affects the concentration of cells that flow through the collect port. You can use the up and down arrows to change
the collection preference during the run to accommodate the conditions of the patient’s blood and achieve the
desired outcome of the procedure.
The default collection preference for a PMN collection procedure is 60. While establishing the initial interface or
while re-establishing the interface after a pump pause or a centrifuge stop, the system targets a higher preference to
avoid collecting non-target cells before the interface is stable. The collection preference that the system targets
depends on whether or not you change the preference before the interface is established.
•
If you do not change the collection preference, the system targets a collection preference of 70.
•
If you change the collection preference, the system targets a collection preference that is about 10 points
higher than the number that you selected, but is not less than a preference of 65.
Once the interface is established, the system gradually decreases the collection preference either to the default or to
the number that you selected. For more information about optimizing the collection preference during the run, see
“Optimizing the Collection Preference” on page 173.
Trend graph
The trend graph shows the status of the collection. It represents an area of the buffy coat that is in the connector.
The horizontal black line on the graph indicates the current collection preference. The green diamonds indicate the
concentration of cells flowing through the collect port as compared to the collection preference.
If the system is unable to collect cells at the target collection preference, the green diamonds could appear above or
below the black line. As long as the diamonds appear in a controlled path within 20 units either above or below the
line, the run is progressing as intended.
Return to patient and collect into bag buttons
The position of the collect valve determines whether the system is directing the flow of cells in the collect line back
to the patient or into the collection bag. The system indicates the current position of the collect valve by showing
the corresponding button on this screen in a touched (lowered) position. You may manually change the position of
the collect valve at any time during the run.
SpectraOptiaOpsManual.book Page 171 Thursday, May 17, 2018 11:24 AM
