Roche Nimblegen MS 200, Руководство оператора

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4 | NimbleGen MS 200 Microarray Scanner Operator’s Manual v1.0
File Size (MB)
Resolution (µm)
Single Channel Dual Channel
Processing Time
(min)
2 630 1260 25
5 100 200 12
10 25 50 8
20 6 12 6
40 2 3 5
ILC Module
For periodic testing of the Microarray Scanner’s performance, the
Microarray Scanner includes an internal Integrated LaserCheck (ILC)
module. The ILC slide, which is used by this module, is provided with the
Microarray Scanner (refer to page 27 for information on how to load the
ILC slide and run the ILC module). The ILC module is designed for
durability, contains no degradable parts, and requires no consumables.
The ILC module checks whether the Microarray Scanner is operating
according to determined parameters within defined limits. The ILC module
should be run on a regular basis. Roche NimbleGen recommends a period
of time of 2 weeks.
Once you initiate the ILC run, the ILC module runs fully automated with no
user intervention. The instrument software will automatically load and
unload the ILC slide as required and perform and evaluate all tests. The
following tests are performed, and results are reported (refer to page 29 for
information on how to save the results):
Actuators Test . Performs a step-loss check for each actuator (e.g. slide
transport, filter wheels).
Barcode Reader Test . Verifies the functionality of the barcode reader.
Oscillator Test . Checks the functionality of the oscillator subsystem and
measures the following: (1) the frequency of the oscillator subsystem and
the presence of the encoder signal at medium and accelerated frequency,
(2) the maximum magnitude of the pixel jitter, and (3) the deviation
perpendicular to the scanning direction (stagger).
Electronics Test . Measures the electronic noise and determines the integrity
of the detection electronics (analog integration, connections, A/D
conversion). Data acquisition is performed with closed detector and gain set
to zero.