ThermoFisher Scientific Vanquish VH-D10, Operating Manual

Page: 171 / 196

8 • Troubleshooting
Vanquish Diode Array Detectors (VH-D10) Operating Manual Page 171
8.3 Checking the Flow Cell
When
Related messages that require a flow cell check appear in the Audit Trail.
For the messages that require checking the flow cell, see
section 8.2
Messages, page 167 .
Follow these steps
1. Check that the flow cell is installed properly. Remove and install the
flow cell.
2. Flush the flow cell with pure LC/MS-grade water at a flow rate of
> 1 mL/min for several minutes.
3. Install a different flow cell or, if available, a diagnostic cell. Repeat
the action during which the message appeared with the different
flow cell or diagnostic cell.
♦ If the message disappears with a different flow cell
The problems are caused by the flow cell that was previously
installed or the flow path or components in the flow path before
the detector. If you suspect a contamination or an elevated
backpressure in the flow cell, perform a back-flushing procedure
with the flow cell that was previously installed (see
section 7.8,
page 134 ).
♦
If the message still appears
Follow the additional assistance instructions for your message in
section
8.2, page 167 .