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CHAPTER

–

REAGENTS

4 . 1

–

O M P A T I B L E

E A G E N T S

The following reagents can be utilized in the ATP



without

any risk of damage:

•

Water

•

Formalin

•

Ethyl alcohol (pure or denatured)

•

Methyl alcohol

•

Isopropanol

•

Butanol

•

Xylene

•

Toluene

•

Paraffin Wax

The following materials are used in the construction of the ATP



. Reagents other

than those listed above can be utilized in the instrument if they

NOT

damage the

materials listed:

Stainless steel

Rotating valve, Retort and lid

Teflon

Rotating valve, air pump

Kynarflex

Reagent pipes

Viton

Membranes

Glass

Vapor trap

HDPE

Paraffin and reagent bottles

Nylon

Connectors

Tygon

Air pipes

Nickel-plated brass

Air connectors, solenoid valves

The manufacturer is

NOT

responsible for damages due to the use of reagents

NOT

listed here.

Содержание ATP1-120

Страница 1: ...14 CROASDAILE DRIVE DURHAM NC 27705 2507 USA 919 384 9393 FAX 919 384 9595 E MAIL tbs trianglebiomedical com ATP Tissue Processor Catalog ATP1 120 ATP1 220 Operations Manual Version 5 3 May 2006 Be ce...

Страница 2: ...l electronic sensors protect the instrument s critical components The ability to optimize each step of every program will allow you to create programs that yield excellent reproducible results consist...

Страница 3: ...3 Transportation 8 CHAPTER3 INTRODUCTIONTOTHEATP PROCESSOR 9 3 1 General Features 9 3 2 Front View 10 3 3 Rear Panel Floppy Drive 11 Floppy Drive 11 CHAPTER 4 REAGENTS 12 4 1 Compatible Reagents 12 4...

Страница 4: ...rsed 29 CHAPTER 9 REAGENT MANAGEMENT SYSTEM RMS 30 9 1 Introduction 30 9 2 Choosing the RMS Mode 31 9 2 1 RMS Single Mode Description and Example 32 9 2 2 RMS Group Mode Description and Example 33 Exa...

Страница 5: ...the Retort Purge Cycle 49 CHAPTER 11 ALARMS 51 11 1 Managing Alarms 51 Non Blocking Alarms 51 Blocking Alarms 51 11 2 Non Blocking Alarms 52 1 BLACK OUT 52 2 RETORT T LOW 53 3 SHORT DRAIN 53 4 P V TIM...

Страница 6: ...er Service Tests 61 Vacuum test 61 Pressure Test 62 Retort Heating 62 Runtime Test 62 Edit Setup 62 Reset Flag 62 Alarms Reset 62 12 2 Service Menu Abbreviation List 63 12 3 Service Assistance 63 CHAP...

Страница 7: ...15 2 Remote Alarm and Auto dialer 69 APPENDIX 1 ACCESSORIES AND SPARE PARTS 70 APPENDIX 2 ATP TECHNICAL DATA SHEET 71 APPENDIX 3 ATP FEATURES 72 APPENDIX 4 ATP PROGRAM MENU FLOW 73 CONTACT INFORMATION...

Страница 8: ...engineers with the input of service and laboratory technicians The number one priority was to produce the most dependable tissue processor on the market After getting to know your instrument we trust...

Страница 9: ...ue to improper or inexperienced use of the instrument 1 1 RE G U L A T O R Y CO M P L I A N C E SAFETY QUALITY STANDARDS The ATP has been tested by a registered independent body to rigorous internatio...

Страница 10: ...US 6 780 380 B2 1 3 SY M B O L S A N D CO N V E N T I O N S Do not use free flame near the instrument No smoking near the instrument Recyclable High voltage Important safety notice Important operatio...

Страница 11: ...nt Valve PV1 Pressure Valve SdO Overfill Sensor SdP Rotating Valve Position Sensor SGR Reagents Management System VR Rotating Valve VT Vapor Trap VV1 Vacuum Valve WPC Paraffin Wax Purification Cycle R...

Страница 12: ...r operative precautions the power switch is placed at the rear of the instrument on the right hand side at approximately the same height as the screen in the front Always make certain to correctly eng...

Страница 13: ...ordance with all applicable laws and ordinances Access to the instrument s internal components is reserved only to those specialists trained in the service of the instrument Always disconnect the proc...

Страница 14: ...ping crates and packing material DO NOT unpack the instrument if damage is apparent Immediately notify the carrier of any damage and contact the shipper to initiate any claims 2 1 UN P A C K I N G The...

Страница 15: ...ing shipping 5 Using the original box or another box adapted to carry the instrument horizontally lay the carton on its back after having properly wrapped and packaged the instrument with care 2 3 TR...

Страница 16: ...unction emptying filling etc Retort and paraffin heating chamber temperatures Retort pressure completion time and date In the event of blackouts the computer saves all the data necessary to restart th...

Страница 17: ...10 3 2 FR O N T VI E W Tilting color touch screen Retort Heated paraffin chamber 5 bottles Reagent bottle chamber Charcoal filter bottles Floppy drive...

Страница 18: ...Alarm pins 1 2 open pins 1 3 closed Please note The socket at E is a low voltage connection maximum 48V 6A isolated from the rest of the instrument An Auto Dialer or other external alarm notification...

Страница 19: ...e construction of the ATP Reagents other than those listed above can be utilized in the instrument if they DO NOT damage the materials listed Stainless steel Rotating valve Retort and lid Teflon Rotat...

Страница 20: ...s fluid Trichloroacetic acid Bouin s fixatives Little s alcoholic lead Trichloroethane Carnoy s fluid Olmacher fluid Weigirt lodine Carnoy Lebrum fluid Osmic acid Zambini s PAF Cedarwood oil Paraforma...

Страница 21: ...er spikes Use of a UPS is highly recommended for sites which experience brown outs or other power fluctuations The use of adapters to plug in more than one instrument to the same outlet power strip do...

Страница 22: ...reen select Service Vacuum Test Perform a vacuum test to confirm the operation of the pumps and sensors associated with the vacuum system 9 From the Main screen select Service Retort Heating Perform a...

Страница 23: ...lure to fill to the correct level can result in errors and alarms 2 Inspect the Quick connect O rings and inspect the internal tubing connection to ensure there are no cracks or defects and that the O...

Страница 24: ...illing of bottles simple and convenient DO NOT use paraffin that is not completely melted It can result in a clogging of the tubing Attempting to fill the bottles with flakes frequently results in an...

Страница 25: ...ent with subsequent scaling of the remaining reagents is preferable to the weekly substitution of all reagents In this way the process quality remains constant while in the latter method process quali...

Страница 26: ...hat should be set by the Supervisor Reagent Names The list of available reagents contains default identifications for quality assurance testing The user can add the names of other reagents to this lis...

Страница 27: ...ent through the menus and the program displays VACUUM RELEASE Vacuum release in the Retort CLEAN Retort washing Purge Cycle ESC Back to main menu stop process etc Above the buttons two message lines d...

Страница 28: ...to change or add on Use and to access the alphabetical list until the letter you want is displayed Use VACUUM RELEASE to select upper case lower case and numbers Use ENTER to confirm and save changes...

Страница 29: ...s the alphabetical list until the letter you want is displayed Use VACUUM RELEASE to select upper case lower case and numbers Use ENTER to confirm and save changes Use ESC to abort the operation All t...

Страница 30: ...The reagents for the Purge Cycle are managed by the RMS It is necessary that the RMS be active in order to receive reminders to substitute the Purge reagents every 3 to 9 processes The recommended nu...

Страница 31: ...that if the instrument is completely reset as explained in Chapter 7 Alarms this default CCW temperature will return to 60 C 7 9 CH A R C O A L FI L T E R LI M I T SE T T I N G The charcoal filters ar...

Страница 32: ...ss contamination This removal is accomplished by a flow of air bubbled through the paraffin containers The volatile reagents evaporate due to the heating of the paraffin containers during the WPC proc...

Страница 33: ...nction This in turn assists service personnel in diagnosing the instrument s problem 7 10 1 MANUAL ST A R T O F T H E WPC If for any reasons the WPC has been interrupted or not allowed to start automa...

Страница 34: ...T PROGRAMS from the MAIN menu 2 From the menu on the right side of the screen use the arrows to select which program you would like to edit Once highlighted press ENTER The Edit Programs Screen will a...

Страница 35: ...the reagent filling and emptying process T e m p The selectable reagent temperature range is Ambient 45 C The selectable paraffin temperature range is 52 60 C P V The Pressure Vacuum P V field allows...

Страница 36: ...ckwards REVERSED It is not possible to insert a delay on the first step The operator cannot modify its name Its position in the list of the processes is always 13 Except as specified above it is ident...

Страница 37: ...quality assurance documentation of reagent bottle status This results in substantial time savings and reduces the possibility of errors when multiple operators use the instrument When activated follow...

Страница 38: ...tification of the bottle are the same plus the reagent is identified by its specific name i e 70 alcohol xylene etc Group mode The intent of the Group mode is to automate the reagent management proces...

Страница 39: ...ubstitution of reagents after a process it is possible to press the ESC key skip this session of the RMS and postpone it until the end of the next process Please note The process limit counters are no...

Страница 40: ...to identify the contents of the bottle but it is classified as part of a group of similar reagents The position number of a reagent bottle does not correspond to the program step number with the excep...

Страница 41: ...ll be prompted to change the most contaminated bottle in the set the first bottle following the first run The second bottle is then accessed first on the next run and would become the next bottle to b...

Страница 42: ...reagents The RMS Instructional Screen indicates what action to take Similar to Single Bottle mode at the end of a process the RMS will prompt the user with graphics and text to replace a reagent bottl...

Страница 43: ...e arrow key to proceed to the definition of the next reagent bottle G r o u p M o d e The contents of each bottle are classified according to the type of reagent not the specific reagent Thus each pos...

Страница 44: ...requency of reagent substitution It is possible to assign each bottle a limit based on the number of processes performed and or a limit based on the number of cassettes processed When one of the two l...

Страница 45: ...etween Single and Group mode Each time the RMS is activated or deactivated When the definition and or limits of the groups are modified Please note Resetting the counters to zero does not occur automa...

Страница 46: ...de 9 7 PR I N T I N G ME N U The Printing Menu From the Printing Menu you may print the following information Alarm Archive Report of the last 100 alarms Setup Parameters Various Instrument Setup Para...

Страница 47: ...gents and reset their process cassette number counters Finally although the user is asked at the end of each process if they would like to print a report of the process just performed it can also be p...

Страница 48: ...d infiltration of wax This can easily be achieved using the spring dividers For maximal capacity the cassettes can be stacked together and held in place with the spring if desired This is shown on the...

Страница 49: ...N G A PR O G R A M Select START PROCESS from the MAIN menu The screen now should look the same as the Edit Program screen Use the and arrows to select the Program that is to be utilized Press ENTER t...

Страница 50: ...he possible presence and duration of any delay in DAYS HOURS and MINUTES The second line will display the time as determined by the computer that the process will be completed Please note The program...

Страница 51: ...er when a program is to be completed The computer stores the hour and or day you have chosen for the process to be completed The next time you choose the same program the computer will indicate the sa...

Страница 52: ...handling midweek holidays Create a third standard program named for example HOLIDAYS where you can set a different completion time to meet the particulars of your schedule Use the Daily setting but b...

Страница 53: ...n the program is started the computer will run a RUNTIME TEST on the main functions of the instrument This test doesn t involve the filling of the Retort and can be stopped at any time by simply press...

Страница 54: ...of a program it is NOT possible to access other functions or edit the program 10 6 IN T E R R U P T I N G T H E PR O C E S S A process can only be aborted when the second message line displays Process...

Страница 55: ...he key VACUUM RELEASE before opening the retort The second message line will then display Normalizing pressure in the retort and after 10 seconds the retort can be opened Within one minute the process...

Страница 56: ...s necessary to do so if paraffin was used during the last step It is preferable to wash the retort even if paraffin has not been used The removal of any paraffin residue before the start of the Purge...

Страница 57: ...leted paraffin processes Take care not to leave fabric or paper residue normally used in cleaning procedures as the material can prevent the complete closing of the main valve membrane with subsequent...

Страница 58: ...l processes the TBS service department should be contacted B l o c k i n g A l a r m s Alarms 11 through 53 are blocking alarms These are true alarms and do interrupt process as the cause of the alarm...

Страница 59: ...ed heating time are NOT considered processing time Cause Loss of power in the lab a blown instrument fuse or merely switching the unit off or jarring the power cord out of the wall or out of the instr...

Страница 60: ...set point temperature during very short steps Cause Incorrect working or damage of temperature sensor heating resistance safety thermostat Solution No intervention by the user is possible If the prob...

Страница 61: ...he first paraffin step 11 the temperature of the paraffin chamber has dropped too low the process will continue until the last reagent If during the draining of the last reagent the problem persists t...

Страница 62: ...ser is possible If the problem persists contact the TBS service department for technical assistance 1 5 T S C O U T Malfunction of the retort temperature sensor Cause TSC sensor failure Solution No in...

Страница 63: ...e Solution No intervention by the user is possible If the problem persists contact the TBS service department for technical assistance 2 0 W A X T L O W During the fill of a paraffin the temperature o...

Страница 64: ...he previous process Cause Due to another alarm or due to an interrupted process the retort is not empty Also caused by neglecting to purge after a process Solution Clean the retort if it is not empty...

Страница 65: ...yboard connector next to the remote alarm connector on the upper rear of the ATP All the functions of the ATP can be operated from the keyboard if the display screen is working but not the touch scree...

Страница 66: ...V E The alarms historical archive is under the SETUP menu and consists of a list of the last 100 alarm occurrences This feature assists a service technician to identify the problem its frequency the s...

Страница 67: ...rocessor Press and hold the green button in the down position Switch on the instrument maintaining the green button in the down position until such time as the Main Menu appears on the LCD screen agai...

Страница 68: ...s running this test should be done with the retort empty The instrument should reach a pressure between 300 and 350mBar TP field within 50 to 60 seconds GRADIENT field If the GRADIENT value exceeds 60...

Страница 69: ...The tests are the same as for the start of a program This function is important to check after a long period of inactivity E d i t S e t u p This is where you can set the following items Language Res...

Страница 70: ...ort 0 If Purge Cycle Run SETP RET Retort temperature set point T DIR RET Retort direct temperature T MED RET Retort average temperature on 20 direct reads T MAX RET Retort maximum temperature raised a...

Страница 71: ...re increase is illuminated In the event of overheating it is best to switch off the instrument and disconnect it completely 13 2 PR O T E C T I O N A G A I N S T EX C E S S PR E S S U R E There is no...

Страница 72: ...and paraffin are at a temperature of 60 C therefore contact with them can cause burns 14 3 PA R A F F I N WA X PU R I F I C A T I O N CY C L E An important addition to the ATP maintenance process is t...

Страница 73: ...lter life will be from 90 120 processes With the use of the WPC filter life will be from 60 90 processes These values are only estimates because they are influenced by Environmental factors humidity t...

Страница 74: ...cated on the rear panel See the illustration in Chapter 3 3 for details There are 4 glass fuses of a 10 Amp 6 x 25 mm rating in holders at the rear or the unit To replace fuses 1 Disconnect the cable...

Страница 75: ...ing on normal paper Roll of inside paper of 25m of easy substitution Cartridge to inky ribbon of easy substitution Extreme compactness could be positioned on the cover of the ATP Speed of printing of...

Страница 76: ...n these contacts they are isolated from the rest of the instrument they can be utilized to activate an external device such as an Auto Dialer to call a pre selected number and relay the message that a...

Страница 77: ...lar cassette capacity 150 with 1 cover 4 dividers and 4 springs Ea ATP1 B150 Basket bulk cassette capacity 200 220 random or 350 stacked with 1 cover Ea ATP1 BB Carrier Handle for easy movement of bas...

Страница 78: ...33 in Width 53 cm 13 5 in Depth 60 cm 15 in Running ambient temperature 10 30 C Storing temperature 0 40 C Sample processing capacity 300 Paraffin temperature warm chamber 50 60 C Paraffin temperatur...

Страница 79: ...he CPU memory is battery backed up In the event of a blackout the processor restarts the process from the interrupted point In the event a BO stops the process during a paraffin step a delay function...

Страница 80: ...73 APPENDIX 4 ATP PROGRAM MENU FLOW...

Страница 81: ...angle Biomedical Sciences Inc 3014 Croasdaile Drive Durham NC 27705 U S A Sales and product information sales trianglebiomedical com Product Service questions service trianglebiomedical com All other...

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