Section I – CD AutoPlus Maintenance
CD14 Tester & CD AutoPlus Autosampler User Guide—75-108-800 Rev. B—31 May 2021
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EAR99 technology subject to restrictions on cover page.
How it Works
The wash routine requires that a wash source be connected to
the CD AutoPlus. The wash source should be clean DI or better
quality water. Other solvents can be used, but Teledyne Hanson
Technical Support should be contacted prior to attempting
washes with more aggressive solvents.
Probes on the CD14 testers are maintained in a raised position
to prevent any contamination caused by media remaining in
vessels that have yet to be cleaned.
The CD AutoPlus will pull from the wash source and pump the
wash solution to each of the testers and the waste lines. To
ensure that all lines reach their specified rinse volumes, a
priming step is performed on the wash lines any time the
needles return to that position. The priming step dispenses out
the probes of the first CD14 Tester (A).
NOTE: It is recommended to have at least 100 mL of volume
available in tester A prior to beginning a wash cycle.
The waste lines are rinsed in the same manner as the testers,
then drained.
After the waste lines are washed, the CD AutoPlus will then pull
from the wash source and dispense out to the dissolution testers
for the specified volume. The volume is specified in multiples of
the syringe capacity.
If programmed, a dry cycle will occur after the testers have been
washed. The dry cycle raises the needles on the AutoFill and
pulls air into the syringes. It then pumps this air out to the
testers, the waste lines, and the wash port. This drying cycle
ensures that no wash solution remains in the lines and that the
system is now ready for another test after the vessels have been
cleaned.
