NuAire LabGard NU-560-400 Operation & Maintenance Manual Download Page 3

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OM0295

Rev 2 September 2020

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ABOUT THIS OPERATION & MAINTENANCE MANUAL

The information contained in this manual is intended to reflect our current production standard configuration model along

with the more frequently purchased options. Any unique additions/modifications/shop drawings are appended in the back flap of

this manual, along with any modifications and/or additions to procedures as outlined in this manual. A copy of the original factory

test report is also appended to this manual. In case this manual and/or test report is lost or misplaced, NuAire retains a copy in our

files. A replacement copy can be obtained by calling or writing NuAire, Inc. stating the model number and serial number and a brief

description of the information desired.

Summary of Contents for LabGard NU-560-400

Page 1: ...nar Flow Biosafety Cabinet Models NU 560 400 600 Bench Console Operation Maintenance Manual Series C Revision 2 September 2020 Manufactured By NuAire Inc 2100 Fernbrook Lane Plymouth MN 55447 Toll Fre...

Page 2: ...om particulate contaminants as prescribed in NSF ANSI 49 Please read this manual carefully to familiarize you with proper installation maintenance and operation of the cabinet Other reference and guid...

Page 3: ...s shop drawings are appended in the back flap of this manual along with any modifications and or additions to procedures as outlined in this manual A copy of the original factory test report is also a...

Page 4: ...ation 7 6 HEPA Filter Leak Test 7 7 Airflow Smoke Pattern Test 7 8 Site Installation Assessment Tests 7 9 Cleanliness Classification Test for Pharmacy Application 7 10 Main Control Board Description R...

Page 5: ...n used with proper technique is an effective laboratory aid in obtaining the optimum control over product quality while reducing the potential for exposure of both product and personnel to airborne bi...

Page 6: ...hile specific agents are used o Which measures are to be taken in the case of an accident Repairs to the device must be carried out only by trained and authorized expert personnel Keep these operating...

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Page 8: ...OM0295 Rev 2 September 2020 Page 8 of 103 2 0 Models Features The model NU 560 LABGARD ES Class II Type B2 Laminar Flow Biosafety Cabinet is manufactured in two sizes 4 ft 1 2m and 6 ft 1 8m...

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Page 11: ...ed Shipments 4 1 1 Terms are factory unless stated otherwise Therefore it is important to check each shipment before acceptance 4 1 2 If there is visible damage the material can be accepted after the...

Page 12: ...accessible If the outlet is inaccessible such as a conduit hardwired connection then an appropriate warning label should be applied near the cabinet s on off switch to indicate the circuit breaker on...

Page 13: ...t is secure See BCD 16300 5 2 2 Leveling Using a level placed on the work tray adjust the leg levelers first end to end then front to back The NSF approved leg levelers provide a 3 4 20mm adjustment 5...

Page 14: ...with the remote controlled needle valve plumbing fixtures NuAire provides for rear bottom or top connections of plumbing services to plant utilities Connection from the needle valve assembly to the w...

Page 15: ...E guide A minimum of 20 gauge for round duct is required to prevent duct collapse due to high static pressure conditions square duct will require heavier gauge material 8 All ductwork should be mainta...

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Page 18: ...st volume and corresponding inflow velocity is displayed on the front panel Preset lower and upper alarm limits are factory set but can be field verified at any time To ensure that adequate exhaust is...

Page 19: ...essure switch operation utilizing independent exhaust volume measurement instrument DIM Per NSF ANSI 49 a 20 loss of exhaust volume must produce an airflow alarm within 15 seconds The testing methods...

Page 20: ...Up to 3 ea Sidewall One Backwall Cabinet Size Inches mm Height Fully Assembled Incl Exh Filter Fastener Height Minimum for Transport Width Depth with Armrest removed 62 1575 62 1575 53 5 8 1362 32 3...

Page 21: ...thermistor airflow sensor in the downflow stream to monitor and control airflow to setpoints The control system automatically compensates for filter loading voltage variances and other environmental...

Page 22: ...us 6 1 3 Run Mode Anytime the blower icon is selected the Run Mode screen will appear The Run Mode screen will display a LFBSC profile and initiate and display the countdown of a 150 second warm up pe...

Page 23: ...y just below the icons is the message area that will indicate alarms errors or other notable conditions Since the message area is limited to one line of text only the highest priority message will be...

Page 24: ...te the Biosafety Cabinet airflow control setpoints Access is restricted to service personnel requiring a service password to change values 6 1 5 2 Timer Settings When pressed timer setting text will p...

Page 25: ...w long the blower will run to purge the cabinet after the blower icon has been pressed to turn OFF the blower Outlet Timer This timer controls how long the outlet remains on after the outlet icon has...

Page 26: ...daily basis the start and stop time of the cabinet To start and stop the cabinets menus that both the blower and LED lights will automatically turn on and off together on a programmed schedule Once in...

Page 27: ...3 6 1 5 3 Historical Performance When press a historical performance text the system displays downflow and inflow history Downflow History press downflow history the system displays the week log data...

Page 28: ...103 Inflow History press downflow history the system displays the week log data in graphical form of Inflow versus days Exhaust History press Exhaust history the system displays the week log data in...

Page 29: ...tion or service personnel to set up and calibrate the cabinet for certification or commissioning 6 1 5 5 Display Setting This menu item provides the ability to alter LCD screen display background cont...

Page 30: ...bility to alter display features and set date time Display Background colors of White Green Blue and Gray can be selected Touch display tone audible feedback can turn on off Display brightness can be...

Page 31: ...et the time and date displayed on the LCD screen Time displayed is real time and will not automatically adjust for day light saving time 6 1 5 6 Change User Password This menu item provides the abilit...

Page 32: ...OM0295 Rev 2 September 2020 Page 32 of 103 Set New Password Retype New Password...

Page 33: ...m s and the display will indicate night setback active The sliding window can be closed and the UV light turned on if installed NOTE If night setback exhaust airflow is reduced by the Building Automat...

Page 34: ...d by appropriate safety personnel 6 2 2 Minimize Penetration of Air Curtain The minimum number of items necessary should be placed into the cabinet to prevent overloading but the work should also be p...

Page 35: ...s This precaution is merely an extension of good aseptic technique as practiced on open bench tops The good laboratory practices designed to minimize creation and or release of aerosols to the environ...

Page 36: ...open face as possible 6 3 4 Air Purge Additional purging of the workspace without user activity should be allowed for 2 3 minutes after materials and apparatuses have been placed in it This will rid...

Page 37: ...binet is provided with a forearm support on the work access opening Periodic mini breaks during work practice should be taken resting forearm to avoid stress and fatigue Effective workzone layout Alwa...

Page 38: ...tection is compromised and a full faced HEPA filtered respirator must be worn c Clean all readily accessible surfaces of the cabinet d Remove perforated metal diffuser screen from the underside of the...

Page 39: ...ume of the sample chamber in the safety cabinet that is to be disinfected The formaldehyde evaporates immediately after reaching its boiling point the minimum reaction time is 6 hours Therefore the fo...

Page 40: ...roblems Normally no preventive maintenance is required on the interior of the cabinet i e the area behind the access panel containing the HEPA filters and motor blower assembly All required adjustment...

Page 41: ...ity of the exhaust system 7 3 1 Supply Filter Replacement see Drawing BCD 19032 Disconnect electrical power from the cabinet before attempting any maintenance action Step 1 Remove screws at each upper...

Page 42: ...ten HEPA seal frame clockwise until the gasket is visually depressed by 1 8 inch 3mm The procedure for replacing the exhaust filter with the Bag in Bag out option is shown on Drawing BCD 05660 7 3 3 M...

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Page 44: ...and that the airflow monitor sensors are calibrated to read the correct values Press MENU to access Calibration Service parameter Entry into the Calibration Service functions requires a service passwo...

Page 45: ...ied in the control system and is factory set and shouldn t require alteration The cabinet type default information controls unit of measure setpoints and limits based on the type and size of cabinet T...

Page 46: ...downflow area workzone exhaust duct diameter size or special work access opening window height these must be entered into the control system to assure the correct display values Press MENU to access...

Page 47: ...ified or altered Typically these default values are factory set based on the cabinet type model and size as previously discussed However they may be altered in special cases for modified cabinets The...

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Page 49: ...ues for NU 560 600 Downflow setpoint 60 Downflow setpoint 60 Downflow high limit 66 Downflow high limit 66 Downflow low limit 54 Downflow low limit 54 Exhaust setpoint 740 Exhaust setpoint 1122 Exhaus...

Page 50: ...ts are necessary for proper cabinet performance The cabinet is considered to be certifiable if the following airflow measurements are present a Downflow average 60 LFPM 5 LFPM 30 m s 025 m s b Inflow...

Page 51: ...correct inflow velocity Use Table 7 1 to relate downflow and exhaust inflow volumes and corresponding average airflow velocities It is always desirable to achieve airflow values that are set as close...

Page 52: ...point stated below Model Low Alarm Limit Pressure Switch Low Trip Point CFM CMH CFM CMH NU 560 400 629 1069 529 899 NU 560 600 954 1621 854 1451 If present remove cardboard from supply air intake and...

Page 53: ...ide of the cabinet Access sensor setup menu Step 2 Access calibrate downflow sensor menu and spot check a few downflow points to verify downflow is close to the desired setpoint of 60 fpm 5 fpm Adjust...

Page 54: ...ocities It is always desirable to achieve airflow values that are set as close as possible to nominal If the inflow velocity is calibrated at the outer edge of the range a greater chance for alarm con...

Page 55: ...ure switch adjustment Pressure switch must be adjusted while control box is open Adjust as needed the adjustment dial until the internal supply blower motor is deactivated Then raise the exhaust volum...

Page 56: ...both the supply duty cycle and the new calibrated downflow value Now the downflow monitor sensor has been calibrated to the actual measured average downflow velocity The cabinet will now control to th...

Page 57: ...d proceed to step 2 If using the display icon enable night setback option by performing the following Turn ON night setback option When the Night Setback option ON the Night Setback icon will appear O...

Page 58: ...the following values which represents approximately 100 fpm 51m s inflow or may be set at any other values within the damper operational range of 30 to 80 NU 560 400 270 CFM 459 CMH NU 560 600 410 CFM...

Page 59: ...exhaust filter is checked using a gross leak method since the exhaust filter is not easily scanned when connected to an exhaust system It may be leak tested by drilling a hole in the duct at a downstr...

Page 60: ...ediately below the wiper gasket The criteria used to evaluate the smoke patterns is the following 1 The smoke inside the cabinet shall show smooth downward flow with no dead spots or reflux 2 No smoke...

Page 61: ...nt test using non hazardous materials A minimum of three 3 1 minute particle counts shall be sampled and recorded while the user simulates aseptic compounding manipulations At Rest Particle Count Test...

Page 62: ...blower should be turned on thus the inflow volume balanced with the downflow volume can be measured to set the desired average inflow velocity The inflow exhaust volume is measured by using a Direct I...

Page 63: ...8 49 73 8 1263 53 89 6 1369 58 05 4 1475 62 21 2 1580 66 37 5 1686 Number of Readings Average Velocity of Constricted Area ft min mps 1 Average Velocity of Constricted Area fpm m s 2 X Constricted Acc...

Page 64: ...the table for the nominal average velocity the calibrated exhaust value entered should be 740cfm 1257CMH NOTE 2 For additional guidance the values provided below with a constant 60fpm 30mls downflow v...

Page 65: ...SIZE 1 4 X 1 1 4 INCH 5 X 20MM 5 X 20MM NU 560 400 10 AMPS 3 AMPS 1 AMP NU 560 600 10 AMPS 3 AMPS 1 AMP 7 10 3 Main Control Board Replacement Note All setup and calibration data will be lost the memo...

Page 66: ...s an error in operation Cabinet type motor type and calibration data will not be affected with this reset Master Reset Resets all calibration cabinet type motor type sensor data and options settings b...

Page 67: ...OM0295 Rev 2 September 2020 Page 67 of 103 Select desired function from menu Perform either reset function as selected below...

Page 68: ...isplay screen will revert back to the NuAire logo main menu At this point the cabinet MUST be turned off to complete the process Either unplug the cabinet or use the power switch within the control ce...

Page 69: ...til key matches push in and turn the locking ring clockwise until ring locks Proceed to calibrate sensor menu 7 11 2 Exhaust Pressure Sensor The exhaust pressure sensor is a digital differential veloc...

Page 70: ...le alarm will be on for 30 seconds upon initial alarm condition then once every ten seconds When presented with an error message please perform the following Step 1 NOTE ALL ERROR MESSAGES Error messa...

Page 71: ...mote override is activated preventing the usage of the cabinet Power Loss Alert Indicates a power interruption has occurred Press DISPLAY to clear message Cabinet outlets won t turn on Check outlet fu...

Page 72: ...access Calibration Service parameter Entry into the Calibration Service functions requires a service password for entry After pressing the Calibration Service menu item a password screen will appear...

Page 73: ...tember 2020 Page 73 of 103 8 2 2 Calibration Service Menu The Calibration Service menu provides a list of sub menu items to accomplish all service tasks Each sub menu item will be described in the fol...

Page 74: ...manual control is on the downflow and inflow displays will indicate nominal setpoints Airflow adjustments can be made in the manual mode by going into airflow calibration and adjusting the blower duty...

Page 75: ...This parameter allows for the selection of time programmable from 30 to 240 seconds determining how often the exhaust controller updates the control signal to the automatic damper i e NU 951 012 if in...

Page 76: ...id having a constant exhaust alarm when the exhaust system is turned off Valid settings for the exhaust control damper position are open close freeze or off Off keeps the exhaust control alarms active...

Page 77: ...U 951 damper function will close during a remote override contact closure However this option allows the opposite damper functio 8 2 2 2 Service The service setup menu allows a QUALIFIED TECHNICIAN to...

Page 78: ...or reset both UV light and motor blower run timer Select desired run time parameter from menu UV Run Time Quantity of hours the UV light has logged ON Reset time for UV lamp replacement Motor Blower...

Page 79: ...has a feature to indicate an advance notice that re certification is due Press DUE to enter into the certification required time period screen Select desired interval of certification required i e No...

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Page 81: ...to set the filter status data used to predict filter life availability Filter status is based on maximum RPM minus the starting RPM entered by technician then scaled to current RPM to determine filte...

Page 82: ...efault conditions as shown Alarm Setup Alarm Silence This parameter allows for the selection of the alarm silence key function When the alarm silence function is on all current and future alarms will...

Page 83: ...hall be silenced The time is displayed in minutes with a programmable range of 1 to 60 Downflow Alarm Time This parameter allows for the selection of time to determine how many continuous seconds of a...

Page 84: ...OM0295 Rev 2 September 2020 Page 84 of 103 Interlock Features All interlocks are enable disabled by a user through the display...

Page 85: ...TOUCHLINK system UV window interlock there is a double redundant UV window interlock relay To override the UV window interlock for service purposes only both interlocks must be changed through the TO...

Page 86: ...lower switch is pending or blue the fan relay will be on or energized In either case the fan relay will be on when the blower switch is on or green and off when the blower switch is off or not colored...

Page 87: ...res This menu item provides the access to aux relay function and accessory outlet functions Aux Relay function This parameter allows for the selection of the AUX relay function When the AUX relay is o...

Page 88: ...these has its own menu screen to excise the control system Select menu screen as desired Blower Sensor Diagnostics Test outputs allow a service technician to exercise these output functions Pressing T...

Page 89: ...agnostic Read inputs all a service technician to exercise or check these input functions The inputs may be checked by altering the state of the input function i e sliding window position and monitorin...

Page 90: ...2 minutes and then remove This action will cause the cabinet to go into a downflow alarm condition The exhaust airflow reading should increase during this test However the downflow reading should go d...

Page 91: ...rammed to aid the supply On Off and exhaust delay options The relay will activate whenever the blower is turned on and stay on unless after 5 minutes there is a low exhaust alarm then the relay will d...

Page 92: ...et or that personnel leave the cabinet face area 10 1 2 Operation The operation of the ultraviolet light is accomplished by closing the sliding window and pressing the UV switch location on the front...

Page 93: ...Strep hermolyticus alpha type 5 500 Staphylococcus aureus 6 600 Staphylococcus albus 5 720 Micrococcus sphaeroides 15 400 Sarcina lutea 26 400 Pseudomonas fluorescens 7 040 Escherichia coli 7 040 Pro...

Page 94: ...h laboratories and most industrial laboratories the expected transient over voltage is 2500 V for a 230 V supply and 1500 V for a 120 V supply 11 5 Pollution Degree 2 0 Pollution degree describes the...

Page 95: ...less Steel Worksurface Stainless Steel Window Faring Stainless Steel Window Glides HDPE Window Safety Glass Window Frame Stainless Steel Front Service Panel Painted Steel Front Decorative Panel Painte...

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