Waters Xevo TQD, Operator'S, Overview And Maintenance Manual

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1-14 Specifications and Operating Modes
MS operating modes
The following table shows the MS operating modes.
In MS mode, the instrument can acquire data at scan speeds as high as
10,000 Da/s. Use this mode for instrument tuning and calibration before
MS/MS analysis. See the mass spectrometer’s online Help for further
information.
Use the selected ion recording (SIR) mode for quantitation when you cannot
find a suitable fragment ion to perform a more specific multiple reaction
monitoring (MRM) analysis (see page 1-15 ). In SIR and MRM modes, neither
quadrupole is scanned, therefore no spectrum (intensity versus mass) is
produced. The data obtained from SIR or MRM analyses derive from the
chromatogram plot (specified mass intensity versus time).
MS operating modes:
Operating mode MS1 Collision cell MS2
MS Pass all masses Resolving
(scanning)
SIR Resolving (static) Pass all masses