Waters Xevo TQD, Operator'S, Overview And Maintenance Manual

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Cleaning the extraction cone 4-41
• Ultrasonic bath.
• Source of oil-free, inert gas (for example, nitrogen) for drying (air-drying
optional).
• Wash bottle containing HPLC-grade (or better) 1:1 methanol/water.
• Large beaker.
To clean the extraction cone
1. Immerse the extraction cone in the glass vessel containing 1:1
methanol/water.
Tip:
If the extraction cone is obviously contaminated, use 45:45:10
methanol/water/formic acid.
2. Place the vessel in the ultrasonic bath for 30 minutes.
3. If you used formic acid in the cleaning solution, do as follows:
a. Rinse the extraction cone by immersing it in a glass vessel
containing water and then placing the vessel in the ultrasonic bath
for 20 minutes.
b. Dry the components by immersing them in separate glass vessels
containing methanol and then placing the vessels in the ultrasonic
bath for 10 minutes.
Warning:
The extraction cone can be contaminated with
biohazardous and/or toxic materials. Always wear
chemical-resistant, powder-free gloves while performing this
procedure.
Warning:
Formic acid is extremely corrosive and toxic. Work with
extreme care, use a fume hood and suitable protective
equipment.
Caution:
The extraction cone is fragile. Never place it on its tip; always
place it on its flanged base.