XVIVO Perfusion System (XPS
TM
) Instructions for Use
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54
-
P/N: 9182
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0189 Revision Q
4.4.2 Impaired LA
Drainage
Check position and patency of
the cannulas.
Confirm correct calibration of
pressure sensors (Sec 3.3.8).
Raising or lowering the hard
shell reservoir will change LA
pressures at approximately
2mmHg/ inch:
The fluid level in
the reservoir should be close to
the same height of the LA.
NOTE: Malposition of the LA
cannula, kinking of the LA or
pulmonary veins, or an airlock in
the system will result in outflow
blockade increasing PAP. The LAP
reading may not change if the
obstruction is proximal to the LA
pressure monitoring cannula.
A positive LA pressure of 3
-
5
mmHg is necessary to protect
the lung. The absence of venous
after
-
load leads to an unstable
geometry of the alveolar
-
capillary space which alters the
pulmonary compliance. LA
pressures greater than 5 mmHg
may prevent cyclic changes of
the lung vasculature during
ventilation.
Troubleshooting
