Waters Xevo TQ-XS Mass, Overview And Maintenance Manual

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1.2.5 Software and data system ...................................................................................................23
1.3 Ionization techniques and source probes......................................................................................23
1.3.1 Electrospray ionization ........................................................................................................24
1.3.2 ESCi.....................................................................................................................................24
1.3.3 APCI ....................................................................................................................................24
1.3.4 Dual-mode APPI/APCI source.............................................................................................24
1.3.5 UniSpray ..............................................................................................................................25
1.3.6 Low-flow ESI probe..............................................................................................................25
1.3.7 NanoFlow ESI source ..........................................................................................................25
1.3.8 Atmospheric solids analysis probe (ASAP) .........................................................................25
1.3.9 APGC...................................................................................................................................26
1.3.10 TRIZAIC UPLC source ......................................................................................................26
1.3.11 ionKey source ....................................................................................................................26
1.4 IntelliStart fluidics system..............................................................................................................26
1.4.1 Overview..............................................................................................................................26
1.4.2 System components ............................................................................................................28
1.4.3 System operation.................................................................................................................28
1.5 Ion optics.......................................................................................................................................28
1.6 MS operating modes .....................................................................................................................29
1.7 MS/MS operating modes...............................................................................................................30
1.7.1 Product (daughter) ion mode ...............................................................................................31
1.7.2 Precursor (parent) ion mode................................................................................................31
1.7.3 MRM mode ..........................................................................................................................32
1.7.4 Constant neutral loss mode .................................................................................................33
1.7.5 Constant neutral gain mode.................................................................................................33
1.7.6 ScanWave daughter scan mode..........................................................................................33
1.8 Leak sensors.................................................................................................................................34
1.9 Vacuum system.............................................................................................................................34
1.10 Rear panel...................................................................................................................................35
2 Preparing the mass spectrometer for operation ...................................................37
2.1 Preparing to start the mass spectrometer .....................................................................................37
2.2 Starting the mass spectrometer ....................................................................................................38
2.3 Verifying the instrument’s state of readiness ................................................................................39
2.4 Monitoring the mass spectrometer LEDs ......................................................................................39
June 9, 2016, 715004990 Rev. A
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