Waters Xevo TQ-XS Mass, Overview And Maintenance Manual

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2
Preparing the mass spectrometer for
operation
This chapter describes how to start and shut down the mass spectrometer.
2.1 Preparing to start the mass spectrometer
This instrument is compatible with the ACQUITY UPLC system; if you are not using an ACQUITY
UPLC system, refer to the documentation relevant to the system you are using (see
Non-
ACQUITY devices for use with the Xevo TQ-XS ).
Notice:
To avoid causing severe damage to the instrument, use only compatible
solvents.
See also:
For more details, refer to the following sources:
• Appendix Materials of Construction and Compatible Solvents of this guide, for mass
spectrometer solvent information.
• Appendix C of the ACQUITY UPLC System Operator's Guide for solvent compatibility with
ACQUITY devices.
To prepare the mass spectrometer:
1. On the rear panel, ensure that the nitrogen supply is connected to the instrument’s nitrogen
inlet connection (see the figure
Connecting the nitrogen gas supply ).
Requirements:
• The nitrogen must be dry and oil-free, with a purity of at least 95% or, for APGC use, at
least 99.999%. Regulate the supply at 600 to 690 kPa (6.0 to 6.9 bar, 90 to 100 psi).
• A gas-fail device must be installed, to interrupt the flow of LC solvent should the
nitrogen supply fail.
2. Ensure that the wash solvent bottle is placed in the solvent tray on top of the instrument
and that the end of the tubing from the fluidics valve is fully submerged in the solvent.
Note:
For additional information on the fluidics connections, see the diagram on the inside
of the fluidics valve access door, and Plumbing schematic .
3. Ensure that the collision gas supply is connected to the instrument’s collision cell gas inlet.
June 9, 2016, 715004990 Rev. A
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