Hologic ThinPrep 5000, Operator'S Manual, Page: 12 / 346

ThinPrep™ 5000 System Instructions for Use English AW-22289-001 Rev. 003 11-2021 6/36
Organism Initial Concentration
Log Reduction After
15 Minutes
HIV-1 3.2 x 10
7
TCID
50
/ml ≥7.0***
Hepatitis B virus
†
2.2 x 10
6
TCID
50
/ml ≥4.25
SARS-CoV-2 virus 1.8 x 10
6
TCID
50
/ml ≥3.75
* After 1 hour 4.7 log reduction
** After 1 hour 5.7 log reduction
*** Data is for 5 minutes
† Organisms were tested with similar organisms from the same genus to
assess antimicrobial effectiveness
Note: All log reduction values with a ≥ designation yielded undetectable microbial
presence after exposure to PreservCyt Solution. The listed values represent the
minimum allowable claim given the initial concentration and the detection limit of
the quantitative method.