Fresenius Medical Care multiFiltrate, Instructions For Use Manual

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Chapter 7: Functional description
7-10 Fresenius Medical Care multiFiltrate IFU-EN-UK 15A-2015
7.2.2 Paediatric CRRT treatments
Special treatment mode for
small children For small children, the desired CRRT efficacy (see Adapting the CRRT
prescription for children on page 7-10) can be obtained by using the
tubing system specially designed for this purpose. Furthermore, the
blood-side fill volume of the tubing system was reduced compared to
the standard consumables.
The Pre CVVH, Post CVVH, and CVVHD treatments can be performed
with the paediatric tubing system.
Treatment parameters
Adapting the CRRT
prescription for children The dose of the renal replacement therapy for a paediatric treatment
can be derived from the recommendations for the treatment of adults by
scaling in accordance with the body surface, for example.
Chadha et al. (chapter 13.4 / no. 11), for example, used a CRRT dose
of 2 l/h / 1.73 m² body surface multiplied with the estimated body
surface of the patient, following the recommendation of Ronco et al. to
use a dose of at least 2 l/h for a typical adult with a body weight of 70 kg.
The value 1.73 m² is the general value for the body surface of a typical
adult.
CVVHD (paediatric) Min. Max. Resolution Unit
Blood flow 10 100 2 ml/min
Ultrafiltration Off / 5 500 5 ml/h
UF goal Off / 10 5000 10 ml
Cont. heparin adm. Off / 0.1 25 0.1 ml/h
Dialysate 100 1500 10 ml/h
Temperature Off / 35 39 0.5 °C
CVVH (paediatric) Min. Max. Resolution Unit
Blood flow 10 100 2 ml/min
Ultrafiltration Off / 5 500 5 ml/h
UF goal Off / 10 5000 10 ml
Cont. heparin adm. Off / 0.1 25 0.1 ml/h
Substituate 100 1500 10 ml/h
Temperature Off / 35 39 0.5 °C