DEVELOPMENTAL TOXICITY: Not available.
The substance may be toxic to kidneys, liver, central nervous system (CNS).
Repeated or prolonged exposure to the substance can produce target organs damage. Repeated exposure to a
highly toxic material may produce general deterioration of health by an accumulation in one or many human
organs.
Section 4: First Aid Measures
Eye Contact:
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Cold water may be used. Get medical attention.
Skin Contact:
In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove
contaminated clothing and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes
before reuse. Get medical attention.
Serious Skin Contact:
Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate
medical attention.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention immediately.
Serious Inhalation: Not available.
Ingestion:
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
clothing such as a collar, tie, belt or waistband.
Serious Ingestion:
Medical Conditions Aggravated by Exposure:
Persons with pre-existiing kidney, respiratory, eye, or neurological problems might be more sensitive to Ethylene
Glycol.
Notes to Physician:
1. Support vital functions, correct for dehydration and shock, and manage fluid balance.
2. The currently recommended medical management of Ethylene Glycol poisoning includes elimination of
Ethylene Glycol and metabolites. Elimination of Ethylene Glycol may be achieved by the following methods:
a. Emptying the stomach by gastric lavage. It is useful if initiated within < 1 of ingestion.
b. Correct metabolic acidosis with intravenous administration of sodium bicarbonate, adjusting the administration
rate accoridng to repeated and frequent measurement of acid/base status.
c. Administer ethanol (orally or by IV (intravenously)) or fomepizole (4-methylpyrazole or Antizol)) therapy by IV
as an antidote to inhibit the ormation of toxic metabolites.
d. If patients are diagnosed and treated early in the course with the above methods, hemodialysis may be avoided
if fomepizole or ethanol therapy is effective and has corrected the metabolic acidosis, and no renal failure is
present. However, once severe acidosis and renal failure occured, however, hemodialysis is necessary. It is
effective in removing Ethylene Glycol and toxic metabolites, and correcting metabolic acidosis.
Section 5: Fire and Explosion Data
Flammability of the Product: May be combustible at high temperature.
Auto-Ignition Temperature: The lowest known value is 398°C (748.4°F) (Ethylene glycol).
Flash Points: CLOSED CUP: 111°C (231.8°F). (Tagliabue.)
Flammable Limits: LOWER: 3.2% (Ethylene Glycol)
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