GE AKTAprocess, Operating Instructions Manual

Page: 172 / 180

8.5 UNICORN method for system CIP/Sanitization/Rinsing
Introduction
This section provides an example of a complete method that may be used for system
cleaning.
Main method
The method outlined here is an example designed for a 2-pump, 10 mm inner diameter
system (max flow 600 l/h). CIP solution in this example is 1 M sodium hydroxide.
The CIP method below does not include the optional sample pump. If a sample
pump is part of the system, it should always be cleaned first. The UNICORN
method must be changed accordingly, so that it starts with the sample pump
inlets.
Note:
(Main)
0.00 Base Time
0.00 Air_Alarm Disabled Disabled
0.00 Gradient 0.0 {%B} 0.00 {base}
0.00 InletCIP InletCIP1
0.00 InletA InletA1
0.00 AirTrap Inline
0.00 Filter Inline
0.00 Column UpFlow
0.00 Outlet Outlet1
0.00 Flow 450 {l/hour}
0.00 Block Fill_CIP_inlet
(Fill_CIP_inlet)
0.00 Base SameAsMain
0.00 InletCIP InletCIP1
1.00 End_Block
0.00 Block Fill_all_A_inlets
(Fill_all_A_inlets)
0.00 Base SameAsMain
0.00 InletA InletA1
0.50 InletA InletA2
172 ÄKTAprocess Operating Instructions 29-0252-49 AA
8 Reference information
8.5 UNICORN method for system CIP/Sanitization/Rinsing