Action
Step
Check that the flow meter signal is stable and has a reasonable reading.
8
Increase the flow rate stepwise to maximum system capacity. Check for
leaks and inspect that pressure sensors and the other instrument readings
(e.g., pH/conductivity) are at an acceptable level.
9
Verify that the air sensor before the column indicates no air (the air sensor
symbol in the UNICORN System Control module flow scheme must be green).
10
Decrease the flow rate to less than 50% of the maximum system capacity
and monitor the flow rate value in the UNICORN System Control module
to verify that the pump(s) regulates down and the rate decreases smoothly.
11
End the manual session (using the END command in UNICORN ) so that the
pump(s) stop and all valves close.
12
The column connections can now be tested for leakage at a flow rate and pressure that
is appropriate for the column/absorbent.
Before putting the column in-line, make sure that the air sensor alarm, for the air sensor
located immediately before the column, is enabled prior to the test
(Alarms:Air_Alarm:Enabled).
120
ÄKTAprocess Operating Instructions 29-0252-49 AA
5 Operation
5.1 Prepare the system
5.1.3 Priming and leakage test
Summary of Contents for AKTAprocess
Page 1: ...GE Healthcare Life Sciences ÄKTAprocess Operating Instructions Original instructions ...
Page 2: ......
Page 179: ......
